Aneurysmal 99m Tc-HMPAO Uptake in Brain Death
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu kazuistiky, časopisecké články
PubMed
38350074
DOI
10.1097/rlu.0000000000005103
PII: 00003072-990000000-00930
Knihovny.cz E-zdroje
- MeSH
- biologický transport MeSH
- dospělí MeSH
- lidé MeSH
- mozek * diagnostické zobrazování MeSH
- mozková smrt * diagnostické zobrazování MeSH
- neurozobrazování MeSH
- SPECT/CT MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
A 41-year-old man was admitted to hospital due to sudden loss of consciousness. A regional brain perfusion SPECT/low-dose CT showed abnormal 99m Tc-HMPAO uptake in the right hemisphere frontotemporally without any other supratentorial or infratentorial radiotracer uptake. A neuropathological examination disclosed a middle cerebral artery aneurysm. Presumably, vessel wall fibrosis prevented collapse. Multiple transmural dissections of the fibrotic aneurysmal wall were the source of the subarachnoid hemorrhage. This interesting image shows that radiotracer accumulation in cerebral artery aneurysms can be a diagnostic pitfall in brain death scintigraphy assessment.
Department of Pathology and Molecular Medicine 3rd Faculty of Medicine Thomayer University Hospital
Department of Radiology General University Hospital Prague Prague Czech Republic
Zobrazit více v PubMed
Sinha P, Conrad GR. Scintigraphic confirmation of brain death. Semin Nucl Med . 2021;42:27–32.
Viderman D, Tapinova K, Abdildin YG. Mechanisms of cerebral vasospasm and cerebral ischaemia in subarachnoid haemorrhage. Clin Physiol Funct Imaging . 2023;43, 1:1–9.
Donohoe KJ, Agrawal G, Frey KA, et al. SNM practice guideline for brain death scintigraphy 2.0. J Nucl Med Technol . 2012;40:198–203.
Rohan Z, Matěj R. The autopsy of the brain and spinal cord in the diagnosis of neurodegenerative diseases—a practical approach to optimize the examination [in Czech]. Cesk Patol . 2015;51:199–204.
Texakalidis P, Sweid A, Mouchtouris N, et al. Aneurysm formation, growth, and rupture: the biology and physics of cerebral aneurysms. World Neurosurg . 2019;130:277–284.
Chen W, Choi EJ, McDougall CM, et al. Brain arteriovenous malformation modeling, pathogenesis, and novel therapeutic targets. Transl Stroke Res . 2014;5:316–329.
Shah R, Miron S, Sodee BD. Visualization of cerebral aneurysm on Tc-99m HMPAO brain perfusion scintigram for brain death. Clin Nucl Med . 1994;19:457–458.
Coelho PBS, Fernandes A, Oliveira A, et al. Brain perfusion SPECT for brain death assessment. Eur J Nucl Med Mol Imaging . 2017;44:350–351.
