Pneumatic Vitreolysis using C3F8 Gas in Treatment Naive Patients with Vitreomacular Traction
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
38997208
DOI
10.31348/2024/34
PII: 137979
Knihovny.cz E-zdroje
- Klíčová slova
- C3F8, Pars plana vitrectomy, intravitreal injection, perfluorocarbons, prospective study, vitrectomy, vitreous detachment,
- MeSH
- fluorokarbony * aplikace a dávkování MeSH
- injekce intravitreální * MeSH
- lidé středního věku MeSH
- lidé MeSH
- následné studie MeSH
- nemoci retiny MeSH
- odchlípení sklivce MeSH
- prospektivní studie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- sklivec MeSH
- zraková ostrost MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- fluorokarbony * MeSH
- perflutren MeSH Prohlížeč
PURPOSE: Evaluation of the effectiveness of pneumatic vitreolysis in disrupting vitreomacular traction in our own cohort of patients. METHODOLOGY: Prospective follow-up of 21 eyes of 18 patients with focal VMT (adhesion width < 1500 µm) who underwent intravitreal injection of 0.3 ml of 100% perfluoropropane between January 2015 and December 2020. The patients were observed for 90 days. RESULTS: Release of VMT was achieved on the 28th day of observation in 15 out of 21 eyes (71.4%), and by the 90th day in 19 out of 21 eyes (90.5%). The average width of adhesion in our patients was 382 µm (±212 µm). Average best corrected visual acuity in our cohort was initially 0.77 (±0.21), after 28 days 0.74 (±0.30), and after 3 months 0.82 (±0.21). At the end of the follow-up period, we did not observe a statistically significant improvement in vision. Macular holes developed in two eyes, but spontaneously closed within 1 month of observation, and no more complications were observed in the cohort. CONCLUSION: Pneumatic vitreolysis by intravitreal injection of C3F8 gas is an effective and inexpensive option for the management of symptomatic vitreomacular traction. The incidence of serious adverse events in our follow-up was significantly lower than in recently published series. The method of management should be selected individually according to the parameters of adhesion, macular hole and associated ocular pathologies.
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