The use of bio-renewable resources as starting materials and reagents in synthetic chemistry is an important area for sustainable development. The use of tetrahydrofuran (THF) and 2-methyltetrahydrofuran (2-MeTHF) is reported, which can be obtained from lignocellulosic biomass, as potential alkylating agents for anilines. The developed N-alkylation process is catalyzed by the readily available cobalt salts and employs industrially available syngas as a reducing agent. The reported approach allows for the green and cost-effective production of N-alkylanilines from readily available feedstocks.

A N Nesmeyanov Institute of Organoelement compounds of the Russian Academy of Sciences Moscow 119991 Russian Federation

Department of Applied Homogeneous Catalysis Leibniz Institut für Katalyse e 5 Albert Einstein Straße 29A 18059 Rostock Germany

Faculty of Chemistry National Research University Higher School of Economics Moscow 101000 Russian Federation

Nanotechnology Centre Centre for Energy and Environmental Technologies VŠB Technical University of Ostrava Ostrava Poruba 708 00 Czech Republic

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