etanercept [Etanercept]

tematický
159
Termíny

Enbrel

 

Enbrel
Erelzi
Etanercept-szzs
Recombinant Human Dimeric TNF Receptor Type II-IgG Fusion Protein
TNF Receptor Type II-IgG Fusion Protein
TNFR-Fc Fusion Protein
TNR 001
TNR-001
TNT Receptor Fusion Protein
TNTR-Fc

Perzistentní odkaz   https://www.medvik.cz/link/D000068800
Definice

A recombinant version of soluble human TNF receptor fused to an IgG FC fragment that binds specifically to TUMOR NECROSIS FACTOR and inhibits its binding with endogenous TNF receptors. It prevents the inflammatory effect of TNF and is used to treat RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS and ANKYLOSING SPONDYLITIS.

DUI
D000068800 MeSH Prohlížeč
CUI
M0276736
Historická pozn.
2016 (1997)
Veřejná pozn.
2016; ETANERCEPT was indexed under IMMUNOGLOBULIN G and RECEPTORS, TUMOR NECROSIS FACTOR 1997-2015

Povolená podhesla

AA
analogy a deriváty 3
AD
aplikace a dávkování 35
CS
chemická syntéza 0
CH
chemie 0
HI
dějiny 0
EC
ekonomika 3
PK
farmakokinetika 4
PD
farmakologie 11
IM
imunologie 2
IP
izolace a purifikace 0
CL
klasifikace 1
BL
krev 0
ME
metabolismus 0
UR
moč 0
CF
mozkomíšní mok 0
ST
normy 0
PO
otrava 0
AE
škodlivé účinky 25
TU
terapeutické užití 70
TO
toxicita 0
RE
účinky záření 0
SD
zásobování a distribuce 0

D Chemikálie a léčiva
D12 aminokyseliny, peptidy a proteiny 16
D12.644 peptidy 1 380
D12.644.541 peptidové fragmenty 357
D12.644.541.500 imunoglobuliny - fragmenty 187
D12.644.541.500.697 imunoglobuliny - Fc fragmenty 48
D12.644.541.500.697.249 CD4 imunoadheziny
D12.644.541.500.697.624 etanercept 159
D12.776 proteiny 2 575
D12.776.124 krevní proteiny 909
D12.776.124.486 imunoproteiny 14
D12.776.124.486.485 imunoglobuliny 1 486
D12.776.124.486.485.538 imunoglobuliny - konstantní oblasti 1
D12.776.124.486.485.538.500 imunoglobuliny - Fc fragmenty 48
D12.776.124.486.485.538.500.249 CD4 imunoadheziny
D12.776.124.486.485.538.500.624 etanercept 159
D12.776.124.486.485.680 imunoglobuliny - fragmenty 187
D12.776.124.486.485.680.697 imunoglobuliny - Fc fragmenty 48
D12.776.124.486.485.680.697.249 CD4 imunoadheziny
D12.776.124.486.485.680.697.624 etanercept 159
D12.776.124.790 sérové globuliny 61
D12.776.124.790.651 imunoglobuliny 1 486
D12.776.124.790.651.538 imunoglobuliny - konstantní oblasti 1
D12.776.124.790.651.538.500 imunoglobuliny - Fc fragmenty 48
D12.776.124.790.651.538.500.249 CD4 imunoadheziny
D12.776.124.790.651.538.500.624 etanercept 159
D12.776.124.790.651.680 imunoglobuliny - fragmenty 187
D12.776.124.790.651.680.660 imunoglobuliny - Fc fragmenty 48
D12.776.124.790.651.680.660.249 CD4 imunoadheziny
D12.776.124.790.651.680.660.624 etanercept 159
D12.776.377 globuliny 68
D12.776.377.715 sérové globuliny 61
D12.776.377.715.548 imunoglobuliny 1 486
D12.776.377.715.548.538 imunoglobuliny - konstantní oblasti 1
D12.776.377.715.548.538.500 imunoglobuliny - Fc fragmenty 48
D12.776.377.715.548.538.500.249 CD4 imunoadheziny
D12.776.377.715.548.538.500.624 etanercept 159
D12.776.377.715.548.680 imunoglobuliny - fragmenty 187
D12.776.377.715.548.680.660 imunoglobuliny - Fc fragmenty 48
D12.776.377.715.548.680.660.249 CD4 imunoadheziny
D12.776.377.715.548.680.660.624 etanercept 159
D12.776.543 membránové proteiny 849
D12.776.543.750 receptory buněčného povrchu 511
D12.776.543.750.705 receptory imunologické 129
D12.776.543.750.705.852 receptory cytokinové 81
D12.776.543.750.705.852.760 receptory TNF 132
D12.776.543.750.705.852.760.048 antigeny CD27 13
D12.776.543.750.705.852.760.072 antigen Ki-1 42
D12.776.543.750.705.852.760.097 antigeny CD40 17
D12.776.543.750.705.852.760.195 antigeny CD95 42
D12.776.543.750.705.852.760.220 antigeny CD137
D12.776.543.750.705.852.760.222 receptor faktoru aktivujícího B-buňky 9
D12.776.543.750.705.852.760.226 maturační antigen B-buněk 15
D12.776.543.750.705.852.760.232 etanercept 159
D12.776.543.750.705.852.760.238 glukokortikoidy indukovaný protein související s TNRF 2
D12.776.543.750.705.852.760.245 receptory lymfotoxinu beta 1
D12.776.543.750.705.852.760.345 protein RANK 17
D12.776.543.750.705.852.760.347 receptory ektodysplasinů
D12.776.543.750.705.852.760.350 receptory OX40 2
D12.776.543.750.705.852.760.396 TRAIL receptory 16
D12.776.543.750.705.852.760.500 receptory faktorů nádorové nekrózy - člen 14
D12.776.543.750.705.852.760.505 receptory faktorů nádorové nekrózy - člen 25
D12.776.543.750.705.852.760.597 receptory TNF - typ I 15
D12.776.543.750.705.852.760.798 receptory TNF - typ II 13
D12.776.543.750.705.852.760.899 receptor TACI 4
D12.776.543.750.705.852.760.949 TNF decoy receptory 3
D12.776.543.750.705.852.760.974 TWEAK receptor

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