C2 Domains [C2 domény]

topical
Terms

C2 doména
C2 doména tensinového typu
C2 doména tenzinového typu

 

C2 Domain
C2 Tensin-type Domain

Persistent link   https://www.medvik.cz/link/D000070538
Definition

Protein modules that function in the targeting of proteins to CELL MEMBRANES. They consist of an eight-stranded anti-parallel beta-sandwich composed of a pair of four-stranded beta-sheets. This structural unit forms a pocket on the membrane-interacting face of the protein and co-ordinates the binding of 2 to 3 calcium ions; however, not all C2 domains bind calcium. Examples of C2 domain-containing proteins include PROTEIN KINASE C and PTEN PHOSPHOHYDROLASE.

DUI
D000070538 MeSH Browser
CUI
M000610798
Previous indexing
Amino Acid Sequence (1990-2016); Protein Binding (1990-2016)
History note
2017
Public note
2017

Allowable subheadings

DE
drug effects 0
GE
genetics 0
IM
immunology 0
PH
physiology 0
RE
radiation effects 0

G Phenomena and Processes
G01 Physical Phenomena 75
G02 Chemical Phenomena 307
G02.111 Biochemical Phenomena 370
G02.111.570 Molecular Structure 1 313
G02.111.570.820 Molecular Conformation 228
G02.111.570.820.709 Protein Conformation 556
G02.111.570.820.709.275 Protein Structural Elements 1
G02.111.570.820.709.275.750 Protein Domains 178
G02.111.570.820.709.275.750.125 C2 Domains
G02.111.570.820.709.275.750.157 Carbohydrate Binding Modules
G02.111.570.820.709.275.750.188 Catalytic Domain 217
G02.111.570.820.709.275.750.219 Discoidin Domain
G02.111.570.820.709.275.750.235 HMG-Box Domains 2
G02.111.570.820.709.275.750.250 Immunoglobulin Domains 4
G02.111.570.820.709.275.750.375 Kringles 2
G02.111.570.820.709.275.750.438 Methyl CpG Binding Domain
G02.111.570.820.709.275.750.469 Pleckstrin Homology Domains 2
G02.111.570.820.709.275.750.477 PR-SET Domains
G02.111.570.820.709.275.750.485 Proline-Rich Protein Domains 3
G02.111.570.820.709.275.750.500 Protein Interaction Domains and Motifs 95
G03 Metabolic Phenomena obsolete
G04 Cell Physiological Phenomena 514
G05 Genetic Phenomena 133
G06 Microbiological Phenomena 95
G07 Physiological Phenomena 175
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 16
G12 Immune System Phenomena 248
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 147
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 129
G17 Mathematical Concepts 66

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