CYS2-HIS2 Zinc Fingers [zinkové prsty C2H2]

topical
Terms

zinkové prsty Cys2His2

 

C2H2 Zinc Fingers
CYS2-HIS2 Zinc Finger Motifs
CYS2HIS2 Zinc Fingers

Persistent link   https://www.medvik.cz/link/D000070580
Definition

A zinc finger motif of approximately 30 amino acids with the general sequence X2-Cys-X2,4-Cys-X12-His-X3,4,5-His that forms a simple beta sheet-beta sheet-alpha helix fold stabilized by zinc ions. It recognizes and binds to a variety of eukaryotic DNA sequences and is very common among sequence-specific DNA BINDING PROTEINS and TRANSCRIPTION FACTORS.

DUI
D000070580 MeSH Browser
CUI
M000611017
Previous indexing
Amino Acid Sequence (1990-2016); Zinc Fingers (1991-2016)
History note
2017
Public note
2017

Allowable subheadings

DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G02.111 Biochemical Phenomena 370
G02.111.570 Molecular Structure 1 314
G02.111.570.820 Molecular Conformation 228
G02.111.570.820.709 Protein Conformation 556
G02.111.570.820.709.275 Protein Structural Elements 1
G02.111.570.820.709.275.500 Amino Acid Motifs 101
G02.111.570.820.709.275.500.985 Zinc Fingers 28
G02.111.570.820.709.275.500.985.250 CYS2-HIS2 Zinc Fingers
G02.111.570.820.709.275.500.985.375 MYND Domains
G02.111.570.820.709.275.500.985.438 PHD Zinc Fingers
G02.111.570.820.709.275.500.985.500 RING Finger Domains 1
G03 Metabolic Phenomena obsolete
G03 Metabolism 1 197
G04 Cell Physiological Phenomena 515
G05 Genetic Phenomena 135
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 17
G12 Immune System Phenomena 249
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 148
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 130
G17 Mathematical Concepts 66

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