Pyrin Domain [PYRIN doména]

topical
Terms

DAPIN doména
PAAD-DAPIN-PYRIN doména
PAAD/DAPIN/PYRIN doména
PYD doména

 

DAPIN Domain
PAAD-DAPIN-PYRIN Domain
PADD Domain
PYD Domain

Definition

A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.

DUI
D000071196 MeSH Browser
CUI
M000613569
Previous indexing
Cytoskeletal Proteins (2001-2016); Protein Structure, Tertiary (2001-2016)
History note
2017
Public note
2017