Sequestosome-1 Protein [sekvestosom 1]

topical
3
Terms

protein sekvestosom 1
sequestosom 1
vazebný protein p62

 

EBI3-Associated Protein of 60 KDa
EBIAP Protein
Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62 Kda
Ubiquitin-Binding Protein p62

Persistent link   https://www.medvik.cz/link/D000071456
Definition

A multidomain protein that is highly conserved among multicellular organisms. It contains a ZZ-type ZINC FINGER domain, C-terminal UBIQUITIN - associated (UBA) domain, and interacts with many other signaling proteins and enzymes including, atypical PROTEIN KINASE C; TNF RECEPTOR-ASSOCIATED FACTOR 6; subunits of the mTORC1 complex, and CASPASE-8. It functions in AUTOPHAGY as a receptor for the degradation of ubiquitinated substrates, and to co-ordinate signaling in response to OXIDATIVE STRESS.

DUI
D000071456 MeSH Browser
CUI
M000614776
Previous indexing
Adaptor Proteins, Signal Transducing (1996-2016); Heat-Shock Proteins (1996-2016)
History note
2017
Public note
2017

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors 1
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 2
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 1
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 383
D12.644.360 Intracellular Signaling Peptides and Proteins 175
D12.644.360.024 Adaptor Proteins, Signal Transducing 182
D12.644.360.024.050 14-3-3 Proteins 76
D12.644.360.024.065 A Kinase Anchor Proteins 1
D12.644.360.024.082 Angiomotins 1
D12.644.360.024.098 Arrestins 6
D12.644.360.024.131 CARD Signaling Adaptor Proteins 7
D12.644.360.024.264 Caveolin 1 14
D12.644.360.024.272 Caveolin 2 1
D12.644.360.024.280 Cortactin 1
D12.644.360.024.282 Crk-Associated Substrate Protein 7
D12.644.360.024.285 Death Domain Receptor Signaling Adaptor Proteins 5
D12.644.360.024.287 Discs Large Homolog 1 Protein
D12.644.360.024.288 Dishevelled Proteins 18
D12.644.360.024.290 GRB2 Adaptor Protein 3
D12.644.360.024.299 GRB7 Adaptor Protein
D12.644.360.024.300 GRB10 Adaptor Protein
D12.644.360.024.301 Insulin Receptor Substrate Proteins 6
D12.644.360.024.302 Interferon Regulatory Factors 11
D12.644.360.024.303 Interferon-Stimulated Gene Factor 3
D12.644.360.024.306 Kelch-Like ECH-Associated Protein 1 9
D12.644.360.024.309 Mediator Complex 5
D12.644.360.024.310 mTOR Associated Protein, LST8 Homolog
D12.644.360.024.311 Myeloid Differentiation Factor 88 16
D12.644.360.024.313 Nod Signaling Adaptor Proteins 1
D12.644.360.024.314 Nuclear Receptor Coactivators 6
D12.644.360.024.315 Nuclear Receptor Interacting Protein 1 3
D12.644.360.024.316 Paxillin 5
D12.644.360.024.318 PII Nitrogen Regulatory Proteins
D12.644.360.024.319 Protein Inhibitors of Activated STAT 3
D12.644.360.024.320 Proto-Oncogene Proteins c-crk 1
D12.644.360.024.321 Proto-Oncogene Proteins c-vav 4
D12.644.360.024.322 Rabphilin-3A
D12.644.360.024.323 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.644.360.024.324 Regulatory-Associated Protein of mTOR
D12.644.360.024.328 Retinoblastoma Binding Proteins 3
D12.644.360.024.329 Sequestosome-1 Protein 3
D12.644.360.024.330 Shc Signaling Adaptor Proteins
D12.644.360.024.332 Signaling Lymphocytic Activation Molecule Associated Protein
D12.644.360.024.334 Smad Proteins 14
D12.644.360.024.342 STAT Transcription Factors 23
D12.644.360.024.374 Suppressor of Cytokine Signaling Proteins 11
D12.644.360.024.437 Syntenins 2
D12.644.360.024.469 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.644.360.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.644.360.024.750 YAP-Signaling Proteins 6
D12.776 Proteins 2 581
D12.776.094 Autophagy-Related Proteins 7
D12.776.094.250 Autophagy-Related Protein 5 3
D12.776.094.391 Autophagy-Related Protein 12 1
D12.776.094.399 Autophagy-Related Protein 7
D12.776.094.407 Autophagy-Related Protein 8 Family 2
D12.776.094.438 Autophagy-Related Protein-1 Homolog 1
D12.776.094.500 Beclin-1 3
D12.776.094.750 Sequestosome-1 Protein 3
D12.776.157 Carrier Proteins 546
D12.776.157.057 Adaptor Proteins, Signal Transducing 182
D12.776.157.057.001 5-Lipoxygenase-Activating Proteins 1
D12.776.157.057.002 14-3-3 Proteins 76
D12.776.157.057.003 A Kinase Anchor Proteins 1
D12.776.157.057.005 Arrestins 6
D12.776.157.057.006 CARD Signaling Adaptor Proteins 7
D12.776.157.057.010 Caveolin 1 14
D12.776.157.057.012 Caveolin 2 1
D12.776.157.057.014 Cortactin 1
D12.776.157.057.016 Crk-Associated Substrate Protein 7
D12.776.157.057.018 Death Domain Receptor Signaling Adaptor Proteins 5
D12.776.157.057.023 Discs Large Homolog 1 Protein
D12.776.157.057.028 Dishevelled Proteins 18
D12.776.157.057.039 GRB10 Adaptor Protein
D12.776.157.057.041 GRB2 Adaptor Protein 3
D12.776.157.057.043 GRB7 Adaptor Protein
D12.776.157.057.045 Insulin Receptor Substrate Proteins 6
D12.776.157.057.050 Interferon Regulatory Factors 11
D12.776.157.057.061 Interferon-Stimulated Gene Factor 3
D12.776.157.057.067 Kelch-Like ECH-Associated Protein 1 9
D12.776.157.057.072 Mediator Complex 5
D12.776.157.057.073 mTOR Associated Protein, LST8 Homolog
D12.776.157.057.074 Myeloid Differentiation Factor 88 16
D12.776.157.057.078 Nod Signaling Adaptor Proteins 1
D12.776.157.057.080 Nuclear Receptor Coactivators 6
D12.776.157.057.086 Nuclear Receptor Interacting Protein 1 3
D12.776.157.057.092 Paxillin 5
D12.776.157.057.110 PII Nitrogen Regulatory Proteins
D12.776.157.057.124 Protein Inhibitors of Activated STAT 3
D12.776.157.057.139 Proto-Oncogene Proteins c-crk 1
D12.776.157.057.144 Proto-Oncogene Proteins c-vav 4
D12.776.157.057.150 Rabphilin-3A
D12.776.157.057.155 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.776.157.057.157 Regulatory-Associated Protein of mTOR
D12.776.157.057.158 Retinoblastoma Binding Proteins 3
D12.776.157.057.160 Sequestosome-1 Protein 3
D12.776.157.057.162 Shc Signaling Adaptor Proteins
D12.776.157.057.166 Signaling Lymphocytic Activation Molecule Associated Protein
D12.776.157.057.170 Smad Proteins 14
D12.776.157.057.186 STAT Transcription Factors 23
D12.776.157.057.249 Suppressor of Cytokine Signaling Proteins 11
D12.776.157.057.374 Syntenins 2
D12.776.157.057.437 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.776.157.057.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.776.157.057.750 YAP-Signaling Proteins 6
D12.776.476 Intracellular Signaling Peptides and Proteins 175
D12.776.476.024 Adaptor Proteins, Signal Transducing 182
D12.776.476.024.034 5-Lipoxygenase-Activating Proteins 1
D12.776.476.024.050 14-3-3 Proteins 76
D12.776.476.024.069 A Kinase Anchor Proteins 1
D12.776.476.024.087 Angiomotins 1
D12.776.476.024.104 Arrestins 6
D12.776.476.024.139 CARD Signaling Adaptor Proteins 7
D12.776.476.024.280 Caveolin 1 14
D12.776.476.024.295 Caveolin 2 1
D12.776.476.024.311 Cortactin 1
D12.776.476.024.316 Crk-Associated Substrate Protein 7
D12.776.476.024.320 Death Domain Receptor Signaling Adaptor Proteins 5
D12.776.476.024.325 Discs Large Homolog 1 Protein
D12.776.476.024.330 Dishevelled Proteins 18
D12.776.476.024.377 GRB2 Adaptor Protein 3
D12.776.476.024.379 GRB7 Adaptor Protein
D12.776.476.024.380 GRB10 Adaptor Protein
D12.776.476.024.381 Homer Scaffolding Proteins 2
D12.776.476.024.382 Insulin Receptor Substrate Proteins 6
D12.776.476.024.385 Interferon Regulatory Factors 11
D12.776.476.024.386 Interferon-Stimulated Gene Factor 3
D12.776.476.024.387 Kelch-Like ECH-Associated Protein 1 9
D12.776.476.024.388 Mediator Complex 5
D12.776.476.024.389 mTOR Associated Protein, LST8 Homolog
D12.776.476.024.390 Myeloid Differentiation Factor 88 16
D12.776.476.024.391 Nod Signaling Adaptor Proteins 1
D12.776.476.024.394 Nuclear Receptor Coactivators 6
D12.776.476.024.396 Nuclear Receptor Interacting Protein 1 3
D12.776.476.024.397 Paxillin 5
D12.776.476.024.400 PII Nitrogen Regulatory Proteins
D12.776.476.024.402 Protein Inhibitors of Activated STAT 3
D12.776.476.024.404 Proto-Oncogene Proteins c-crk 1
D12.776.476.024.407 Proto-Oncogene Proteins c-vav 4
D12.776.476.024.409 Rabphilin-3A
D12.776.476.024.411 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.776.476.024.414 Receptor Activity-Modifying Proteins 1
D12.776.476.024.419 Regulatory-Associated Protein of mTOR
D12.776.476.024.420 Retinoblastoma Binding Proteins 3
D12.776.476.024.422 Sequestosome-1 Protein 3
D12.776.476.024.424 Shc Signaling Adaptor Proteins
D12.776.476.024.426 Signaling Lymphocytic Activation Molecule Associated Protein
D12.776.476.024.428 Smad Proteins 14
D12.776.476.024.430 STAT Transcription Factors 23
D12.776.476.024.437 Suppressor of Cytokine Signaling Proteins 11
D12.776.476.024.468 Syntenins 2
D12.776.476.024.484 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.776.476.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.776.476.024.750 YAP-Signaling Proteins 6

SQSTM1 protein, human Chemical MeSH Browser

SQSTM1 protein, zebrafish Chemical MeSH Browser

Sqstm1 protein, mouse Chemical MeSH Browser

Sqstm1 protein, rat Chemical MeSH Browser

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