Paxillin [paxilin]

topical
5
Persistent link   https://www.medvik.cz/link/D051419
Definition

Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response to integrin-mediated CELL ADHESION, and interacts with a variety of proteins including VINCULIN; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK.

DUI
D051419 MeSH Browser
CUI
M0193207
History note
2006(1991)
Public note
2006; PAXILLIN was indexed under CYTOSKELETAL PROTEINS & PHOSPHOPROTEINS 1991-2005

Allowable subheadings

AD
administration & dosage 1
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 1
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 3
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 383
D12.644.360 Intracellular Signaling Peptides and Proteins 175
D12.644.360.024 Adaptor Proteins, Signal Transducing 182
D12.644.360.024.050 14-3-3 Proteins 76
D12.644.360.024.065 A Kinase Anchor Proteins 1
D12.644.360.024.082 Angiomotins 1
D12.644.360.024.098 Arrestins 6
D12.644.360.024.131 CARD Signaling Adaptor Proteins 7
D12.644.360.024.264 Caveolin 1 14
D12.644.360.024.272 Caveolin 2 1
D12.644.360.024.280 Cortactin 1
D12.644.360.024.282 Crk-Associated Substrate Protein 7
D12.644.360.024.285 Death Domain Receptor Signaling Adaptor Proteins 5
D12.644.360.024.287 Discs Large Homolog 1 Protein
D12.644.360.024.288 Dishevelled Proteins 18
D12.644.360.024.290 GRB2 Adaptor Protein 3
D12.644.360.024.299 GRB7 Adaptor Protein
D12.644.360.024.300 GRB10 Adaptor Protein
D12.644.360.024.301 Insulin Receptor Substrate Proteins 6
D12.644.360.024.302 Interferon Regulatory Factors 11
D12.644.360.024.303 Interferon-Stimulated Gene Factor 3
D12.644.360.024.306 Kelch-Like ECH-Associated Protein 1 9
D12.644.360.024.309 Mediator Complex 5
D12.644.360.024.310 mTOR Associated Protein, LST8 Homolog
D12.644.360.024.311 Myeloid Differentiation Factor 88 16
D12.644.360.024.313 Nod Signaling Adaptor Proteins 1
D12.644.360.024.314 Nuclear Receptor Coactivators 6
D12.644.360.024.315 Nuclear Receptor Interacting Protein 1 3
D12.644.360.024.316 Paxillin 5
D12.644.360.024.318 PII Nitrogen Regulatory Proteins
D12.644.360.024.319 Protein Inhibitors of Activated STAT 3
D12.644.360.024.320 Proto-Oncogene Proteins c-crk 1
D12.644.360.024.321 Proto-Oncogene Proteins c-vav 4
D12.644.360.024.322 Rabphilin-3A
D12.644.360.024.323 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.644.360.024.324 Regulatory-Associated Protein of mTOR
D12.644.360.024.328 Retinoblastoma Binding Proteins 3
D12.644.360.024.329 Sequestosome-1 Protein 3
D12.644.360.024.330 Shc Signaling Adaptor Proteins
D12.644.360.024.332 Signaling Lymphocytic Activation Molecule Associated Protein
D12.644.360.024.334 Smad Proteins 14
D12.644.360.024.342 STAT Transcription Factors 23
D12.644.360.024.374 Suppressor of Cytokine Signaling Proteins 11
D12.644.360.024.437 Syntenins 2
D12.644.360.024.469 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.644.360.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.644.360.024.750 YAP-Signaling Proteins 6
D12.776 Proteins 2 581
D12.776.157 Carrier Proteins 546
D12.776.157.057 Adaptor Proteins, Signal Transducing 182
D12.776.157.057.001 5-Lipoxygenase-Activating Proteins 1
D12.776.157.057.002 14-3-3 Proteins 76
D12.776.157.057.003 A Kinase Anchor Proteins 1
D12.776.157.057.005 Arrestins 6
D12.776.157.057.006 CARD Signaling Adaptor Proteins 7
D12.776.157.057.010 Caveolin 1 14
D12.776.157.057.012 Caveolin 2 1
D12.776.157.057.014 Cortactin 1
D12.776.157.057.016 Crk-Associated Substrate Protein 7
D12.776.157.057.018 Death Domain Receptor Signaling Adaptor Proteins 5
D12.776.157.057.023 Discs Large Homolog 1 Protein
D12.776.157.057.028 Dishevelled Proteins 18
D12.776.157.057.039 GRB10 Adaptor Protein
D12.776.157.057.041 GRB2 Adaptor Protein 3
D12.776.157.057.043 GRB7 Adaptor Protein
D12.776.157.057.045 Insulin Receptor Substrate Proteins 6
D12.776.157.057.050 Interferon Regulatory Factors 11
D12.776.157.057.061 Interferon-Stimulated Gene Factor 3
D12.776.157.057.067 Kelch-Like ECH-Associated Protein 1 9
D12.776.157.057.072 Mediator Complex 5
D12.776.157.057.073 mTOR Associated Protein, LST8 Homolog
D12.776.157.057.074 Myeloid Differentiation Factor 88 16
D12.776.157.057.078 Nod Signaling Adaptor Proteins 1
D12.776.157.057.080 Nuclear Receptor Coactivators 6
D12.776.157.057.086 Nuclear Receptor Interacting Protein 1 3
D12.776.157.057.092 Paxillin 5
D12.776.157.057.110 PII Nitrogen Regulatory Proteins
D12.776.157.057.124 Protein Inhibitors of Activated STAT 3
D12.776.157.057.139 Proto-Oncogene Proteins c-crk 1
D12.776.157.057.144 Proto-Oncogene Proteins c-vav 4
D12.776.157.057.150 Rabphilin-3A
D12.776.157.057.155 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.776.157.057.157 Regulatory-Associated Protein of mTOR
D12.776.157.057.158 Retinoblastoma Binding Proteins 3
D12.776.157.057.160 Sequestosome-1 Protein 3
D12.776.157.057.162 Shc Signaling Adaptor Proteins
D12.776.157.057.166 Signaling Lymphocytic Activation Molecule Associated Protein
D12.776.157.057.170 Smad Proteins 14
D12.776.157.057.186 STAT Transcription Factors 23
D12.776.157.057.249 Suppressor of Cytokine Signaling Proteins 11
D12.776.157.057.374 Syntenins 2
D12.776.157.057.437 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.776.157.057.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.776.157.057.750 YAP-Signaling Proteins 6
D12.776.476 Intracellular Signaling Peptides and Proteins 175
D12.776.476.024 Adaptor Proteins, Signal Transducing 182
D12.776.476.024.034 5-Lipoxygenase-Activating Proteins 1
D12.776.476.024.050 14-3-3 Proteins 76
D12.776.476.024.069 A Kinase Anchor Proteins 1
D12.776.476.024.087 Angiomotins 1
D12.776.476.024.104 Arrestins 6
D12.776.476.024.139 CARD Signaling Adaptor Proteins 7
D12.776.476.024.280 Caveolin 1 14
D12.776.476.024.295 Caveolin 2 1
D12.776.476.024.311 Cortactin 1
D12.776.476.024.316 Crk-Associated Substrate Protein 7
D12.776.476.024.320 Death Domain Receptor Signaling Adaptor Proteins 5
D12.776.476.024.325 Discs Large Homolog 1 Protein
D12.776.476.024.330 Dishevelled Proteins 18
D12.776.476.024.377 GRB2 Adaptor Protein 3
D12.776.476.024.379 GRB7 Adaptor Protein
D12.776.476.024.380 GRB10 Adaptor Protein
D12.776.476.024.381 Homer Scaffolding Proteins 2
D12.776.476.024.382 Insulin Receptor Substrate Proteins 6
D12.776.476.024.385 Interferon Regulatory Factors 11
D12.776.476.024.386 Interferon-Stimulated Gene Factor 3
D12.776.476.024.387 Kelch-Like ECH-Associated Protein 1 9
D12.776.476.024.388 Mediator Complex 5
D12.776.476.024.389 mTOR Associated Protein, LST8 Homolog
D12.776.476.024.390 Myeloid Differentiation Factor 88 16
D12.776.476.024.391 Nod Signaling Adaptor Proteins 1
D12.776.476.024.394 Nuclear Receptor Coactivators 6
D12.776.476.024.396 Nuclear Receptor Interacting Protein 1 3
D12.776.476.024.397 Paxillin 5
D12.776.476.024.400 PII Nitrogen Regulatory Proteins
D12.776.476.024.402 Protein Inhibitors of Activated STAT 3
D12.776.476.024.404 Proto-Oncogene Proteins c-crk 1
D12.776.476.024.407 Proto-Oncogene Proteins c-vav 4
D12.776.476.024.409 Rabphilin-3A
D12.776.476.024.411 Rapamycin-Insensitive Companion of mTOR Protein 2
D12.776.476.024.414 Receptor Activity-Modifying Proteins 1
D12.776.476.024.419 Regulatory-Associated Protein of mTOR
D12.776.476.024.420 Retinoblastoma Binding Proteins 3
D12.776.476.024.422 Sequestosome-1 Protein 3
D12.776.476.024.424 Shc Signaling Adaptor Proteins
D12.776.476.024.426 Signaling Lymphocytic Activation Molecule Associated Protein
D12.776.476.024.428 Smad Proteins 14
D12.776.476.024.430 STAT Transcription Factors 23
D12.776.476.024.437 Suppressor of Cytokine Signaling Proteins 11
D12.776.476.024.468 Syntenins 2
D12.776.476.024.484 Transcriptional Coactivator with PDZ-Binding Motif Proteins 1
D12.776.476.024.500 Tumor Necrosis Factor Receptor-Associated Peptides and Proteins 4
D12.776.476.024.750 YAP-Signaling Proteins 6
D12.776.512 LIM Domain Proteins 10
D12.776.512.124 Lim Kinases 2
D12.776.512.249 LIM-Homeodomain Proteins 5
D12.776.512.374 Paxillin 5
D12.776.512.500 Zyxin
D12.776.744 Phosphoproteins 189
D12.776.744.049 bcl-Associated Death Protein 2
D12.776.744.100 BRCA1 Protein 103
D12.776.744.150 Caseins 80
D12.776.744.287 Caveolin 1 14
D12.776.744.356 Caveolin 2 1
D12.776.744.360 CDC2 Protein Kinase 36
D12.776.744.390 Cortactin 1
D12.776.744.425 Crk-Associated Substrate Protein 7
D12.776.744.459 Dopamine and cAMP-Regulated Phosphoprotein 32 3
D12.776.744.476 Fanconi Anemia Complementation Group A Protein 1
D12.776.744.484 Fanconi Anemia Complementation Group D2 Protein 4
D12.776.744.488 Fanconi Anemia Complementation Group G Protein 2
D12.776.744.493 Focal Adhesion Kinase 1 3
D12.776.744.527 Integrin-Binding Sialoprotein 1
D12.776.744.562 Interferon Regulatory Factor-3 3
D12.776.744.631 Interferon Regulatory Factor-7 3
D12.776.744.665 Paxillin 5
D12.776.744.700 Phosvitin
D12.776.744.736 Plectin 8
D12.776.744.741 Smad Proteins, Receptor-Regulated 1
D12.776.744.747 Retinoblastoma-Like Protein p107 4
D12.776.744.755 Retinoblastoma-Like Protein p130 5
D12.776.744.770 Retinoblastoma Protein 52
D12.776.744.772 Stathmin 4
D12.776.744.840 Synapsins 2
D12.776.744.845 Tumor Suppressor Protein p53 762
D12.776.744.925 Vitellogenins 21
D12.776.744.962 Zyxin

PXN protein, Xenopus Chemical MeSH Browser

PXN protein, human Chemical MeSH Browser

Pax protein, Drosophila Chemical MeSH Browser

Pxn protein, mouse Chemical MeSH Browser

Pxn protein, rat Chemical MeSH Browser

pxna protein, zebrafish Chemical MeSH Browser

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