autofagický protein Atg7 [Autophagy-Related Protein 7]

tematický
Termíny

Atg7
protein Atg7

 

ATG12-Activating Enzyme E1 ATG7
ATG7 Protein
Ubiquitin-Activating Enzyme E1-like Protein
Ubiquitin-Like Modifier-Activating Enzyme ATG7

Perzistentní odkaz   https://www.medvik.cz/link/D000071193
Definice

An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition.

DUI
D000071193 MeSH Prohlížeč
CUI
M000613486
Předchozí užití
Microtubule-Associated Proteins (2005-2016); Ubiquitin-Activating Enzymes (2006-2016)
Historická pozn.
2017
Veřejná pozn.
2017