Autophagy-Related Protein 7 [autofagický protein Atg7]
topical
- Terms
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Atg7
protein Atg7
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ATG12-Activating Enzyme E1 ATG7
ATG7 Protein
Ubiquitin-Activating Enzyme E1-like Protein
Ubiquitin-Like Modifier-Activating Enzyme ATG7
Persistent link
https://www.medvik.cz/link/D000071193
Definition
An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition.
- DUI
- D000071193 MeSH Browser
- CUI
- M000613486
- Previous indexing
- Microtubule-Associated Proteins (2005-2016); Ubiquitin-Activating Enzymes (2006-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.776.094.399
Autophagy-Related Protein 7
D12.776.094.438
Autophagy-Related Protein-1 Homolog