Death Effector Domain [DED doména]

topical
Terms

efektorová death doména
efektorová doména DED
efektorová doména smrti

 

DED Domain

Persistent link   https://www.medvik.cz/link/D000071461
Definition

A homotypic protein interaction module of the death domain superfamily that is composed of a bundle of six alpha-helices. The death effector domain shares sequence and structural similarities with the DEATH DOMAIN and CASPASE RECRUITMENT DOMAIN. It occurs in many proteins with essential functions in APOPTOSIS.

DUI
D000071461 MeSH Browser
CUI
M000614795
Previous indexing
Amino Acid Sequence (1997-2016); Adaptor Proteins, Signal Transducing (1997-2016); Death Domain Receptor Signaling Adaptor Proteins (2007-2016)
History note
2017
Public note
2017

Allowable subheadings

DE
drug effects 0
GE
genetics 0
IM
immunology 0
PH
physiology 0
RE
radiation effects 0

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G02.111 Biochemical Phenomena 370
G02.111.570 Molecular Structure 1 314
G02.111.570.820 Molecular Conformation 228
G02.111.570.820.709 Protein Conformation 556
G02.111.570.820.709.275 Protein Structural Elements 1
G02.111.570.820.709.275.750 Protein Domains 178
G02.111.570.820.709.275.750.500 Protein Interaction Domains and Motifs 95
G02.111.570.820.709.275.750.500.395 Death Domain Superfamily
G02.111.570.820.709.275.750.500.395.250 Caspase Activation and Recruitment Domain
G02.111.570.820.709.275.750.500.395.500 Death Domain
G02.111.570.820.709.275.750.500.395.750 Death Effector Domain
G02.111.570.820.709.275.750.500.395.875 Pyrin Domain
G03 Metabolic Phenomena obsolete
G04 Cell Physiological Phenomena 514
G05 Genetic Phenomena 135
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 16
G12 Immune System Phenomena 248
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 147
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 129
G17 Mathematical Concepts 66

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