Dishevelled Proteins [protein dishevelled]

topical
18
Terms

DVL proteiny
protein DVL1
protein DVL2
protein DVL3
proteiny DVL1-3

 

Dishevelled Protein
Dishevelled-1 Protein
Dishevelled-2 Protein
Dishevelled-3 Protein

Definition

A family of proteins that are key components of the WNT SIGNALING PATHWAY, where they function downstream of FRIZZLED RECEPTORS. They contain an N-terminal dishevelled-AXIN PROTEIN (DIX) domain, which mediates oligomerization; a central PDZ DOMAIN which binds to the frizzled receptor; and a C-terminal DEP domain which facilitates binding to the CELL MEMBRANE. Dishevelled proteins have important functions in CELL DIFFERENTIATION and establishing CELL POLARITY.

DUI
D000072261 MeSH Browser
CUI
M0226765
History note
2017 (1994)
Public note
2017; DISHEVELLED PROTEINS was indexed under ADAPTOR PROTEINS, SIGNAL TRANSDUCING 2006-2016; under PHOSPHOPROTEINS 1998-2016; and under PROTEINS 1994-1997

D Chemicals and Drugs
D12.644 Peptides 1 380
D12.644.360.024.050 14-3-3 Proteins 75
D12.644.360.024.065 A Kinase Anchor Proteins 1
D12.644.360.024.082 Angiomotins 1
D12.644.360.024.098 Arrestins 6
D12.644.360.024.131 CARD Signaling Adaptor Proteins 7
D12.644.360.024.264 Caveolin 1 14
D12.644.360.024.272 Caveolin 2 1
D12.644.360.024.280 Cortactin 1
D12.644.360.024.288 Dishevelled Proteins 18
D12.644.360.024.290 GRB2 Adaptor Protein 3
D12.644.360.024.299 GRB7 Adaptor Protein
D12.644.360.024.300 GRB10 Adaptor Protein
D12.644.360.024.302 Interferon Regulatory Factors 11
D12.644.360.024.309 Mediator Complex 5
D12.644.360.024.313 Nod Signaling Adaptor Proteins 1
D12.644.360.024.314 Nuclear Receptor Coactivators 6
D12.644.360.024.316 Paxillin 5
D12.644.360.024.320 Proto-Oncogene Proteins c-crk 1
D12.644.360.024.321 Proto-Oncogene Proteins c-vav 4
D12.644.360.024.322 Rabphilin-3A
D12.644.360.024.328 Retinoblastoma Binding Proteins 3
D12.644.360.024.329 Sequestosome-1 Protein 3
D12.644.360.024.334 Smad Proteins 14
D12.644.360.024.342 STAT Transcription Factors 23
D12.644.360.024.437 Syntenins 2
D12.644.360.024.750 YAP-Signaling Proteins 5
D12.776 Proteins 2 575
D12.776.157 Carrier Proteins 546
D12.776.157.057.002 14-3-3 Proteins 75
D12.776.157.057.003 A Kinase Anchor Proteins 1
D12.776.157.057.005 Arrestins 6
D12.776.157.057.006 CARD Signaling Adaptor Proteins 7
D12.776.157.057.010 Caveolin 1 14
D12.776.157.057.012 Caveolin 2 1
D12.776.157.057.014 Cortactin 1
D12.776.157.057.028 Dishevelled Proteins 18
D12.776.157.057.039 GRB10 Adaptor Protein
D12.776.157.057.041 GRB2 Adaptor Protein 3
D12.776.157.057.043 GRB7 Adaptor Protein
D12.776.157.057.050 Interferon Regulatory Factors 11
D12.776.157.057.072 Mediator Complex 5
D12.776.157.057.078 Nod Signaling Adaptor Proteins 1
D12.776.157.057.080 Nuclear Receptor Coactivators 6
D12.776.157.057.092 Paxillin 5
D12.776.157.057.139 Proto-Oncogene Proteins c-crk 1
D12.776.157.057.144 Proto-Oncogene Proteins c-vav 4
D12.776.157.057.150 Rabphilin-3A
D12.776.157.057.158 Retinoblastoma Binding Proteins 3
D12.776.157.057.160 Sequestosome-1 Protein 3
D12.776.157.057.170 Smad Proteins 14
D12.776.157.057.186 STAT Transcription Factors 23
D12.776.157.057.374 Syntenins 2
D12.776.157.057.750 YAP-Signaling Proteins 5
D12.776.476.024.050 14-3-3 Proteins 75
D12.776.476.024.069 A Kinase Anchor Proteins 1
D12.776.476.024.087 Angiomotins 1
D12.776.476.024.104 Arrestins 6
D12.776.476.024.139 CARD Signaling Adaptor Proteins 7
D12.776.476.024.280 Caveolin 1 14
D12.776.476.024.295 Caveolin 2 1
D12.776.476.024.311 Cortactin 1
D12.776.476.024.330 Dishevelled Proteins 18
D12.776.476.024.377 GRB2 Adaptor Protein 3
D12.776.476.024.379 GRB7 Adaptor Protein
D12.776.476.024.380 GRB10 Adaptor Protein
D12.776.476.024.381 Homer Scaffolding Proteins 1
D12.776.476.024.385 Interferon Regulatory Factors 11
D12.776.476.024.388 Mediator Complex 5
D12.776.476.024.391 Nod Signaling Adaptor Proteins 1
D12.776.476.024.394 Nuclear Receptor Coactivators 6
D12.776.476.024.397 Paxillin 5
D12.776.476.024.404 Proto-Oncogene Proteins c-crk 1
D12.776.476.024.407 Proto-Oncogene Proteins c-vav 4
D12.776.476.024.409 Rabphilin-3A
D12.776.476.024.420 Retinoblastoma Binding Proteins 3
D12.776.476.024.422 Sequestosome-1 Protein 3
D12.776.476.024.428 Smad Proteins 14
D12.776.476.024.430 STAT Transcription Factors 23
D12.776.476.024.468 Syntenins 2
D12.776.476.024.750 YAP-Signaling Proteins 5