T-Cell Intracellular Antigen-1 [T-buněčný intracelulární antigen 1]
topical
1
- Terms
-
RNA-vázající protein TIA-1
RNA-vazebný protein TIA-1
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RNA-Binding Protein TIA-1
T-Cell-Restricted Intracellular Antigen-1
Persistent link
https://www.medvik.cz/link/D000074019
Definition
An RNA-binding protein characterized by three RNA RECOGNITION MOTIFS. It binds to AU RICH ELEMENTS in the 3'-untranslated regions of mRNA and regulates alternative pre-RNA splicing and mRNA translation; it may also function in APOPTOSIS. Mutations in the TIA-1 gene are associated with WELANDER DISTAL MYOPATHY.
- DUI
- D000074019 MeSH Browser
- CUI
- M000625192
- Previous indexing
- RNA-Binding Proteins (1991-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 1
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.776.157.725.452.125
Ataxin-2
D12.776.157.725.452.500
Poly(A)-Binding Protein II
D12.776.157.725.813.375
Deleted in Azoospermia 1 Protein
D12.776.157.725.829.282
PTB-Associated Splicing Factor
D12.776.664.962.452.125
Ataxin-2
D12.776.664.962.452.500
Poly(A)-Binding Protein II
D12.776.664.962.813.375
Deleted in Azoospermia 1 Protein
D12.776.664.962.829.282
PTB-Associated Splicing Factor