Serine Peptidase Inhibitor Kazal-Type 5 [inhibitor serinových peptidas Kazalova typu 5]
- Terms
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inhibitor serinových peptidáz Kazalova typu 5
protein LEKTI
protein SPINK5
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LEKTI Protein
Lympho-Epithelial Kazal-Type Inhibitor
Serine Protease Inhibitor Kazal-Type 5
SPINK5 Protein
A secreted serine peptidase inhibitor that consists of 15 KAZAL MOTIFS and inhibits KALLIKREINS KLK5, KLK7, and KLK14 as well as TRYPSIN. It plays important roles in protecting MUCOSA against infection and inflammation, and in maintaining the integrity of the skin. Mutations in the SPINK5 gene are associated with NETHERTON SYNDROME.
- DUI
- D000074163 MeSH Browser
- CUI
- M000625733
- Previous indexing
- Carrier Proteins (1999-2017); Proteinase Inhibitory Proteins, Secretory (2005-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
SPINK5 protein, human Chemical MeSH Browser
Spink5 protein, mouse Chemical MeSH Browser