Trypsin Inhibitor, Kazal Pancreatic [inhibitor trypsinu Kazal pankreatický]
- Terms
-
Acidic Pancreatic Trypsin Inhibitor
Inhibitor, Tumor-Associated Trypsin
Kazal Pancreatic Trypsin Inhibitor
Pancreatic Secretory Trypsin Inhibitor
Pancreatic Secretory Trypsin Inhibitor, Kazal
Pancreatic Trypsin Secretory Inhibitor, Kazal
Serine Peptidase Inhibitor, Kazal-Type 1
Serine Protease Inhibitor Kazal-Type 1
SPINK1
Trypsin Inhibitor Kazal Pancreatic
Trypsin Inhibitor, Pancreatic Secretory
Trypsin Inhibitor, Tumor-Associated
Tumor-Associated Trypsin Inhibitor
A secreted KAZAL MOTIF-containing serine peptidase inhibitor that inhibits TRYPSIN. It is a protein composed of 56 amino acid residues and is different in amino acid composition and physiological activity from the Kunitz bovine pancreatic trypsin inhibitor (APROTININ). It protects against the trypsin-mediated premature activation of ENZYME PRECURSORS in the PANCREAS. Mutations in the SPINK1 gene are associated with CHRONIC PANCREATITIS.
- DUI
- D014359 MeSH Browser
- CUI
- M0022080
- Previous indexing
- Pancreatic Juice (1972-1974); Trypsin Inhibitors (1972-1974)
- History note
- 91(75); was see under TRYPSIN INHIBITORS 1975-90
- Public note
- 91; was see under TRYPSIN INHIBITORS 1975-90
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- BI
- biosynthesis 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification 1
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine 1
CPAMD8 protein, human Chemical MeSH Browser
SPINK1 protein, human Chemical MeSH Browser
Spink1 protein, mouse Chemical MeSH Browser
Spink1 protein, rat Chemical MeSH Browser
acrosin inhibitor, porcine Chemical MeSH Browser
ovomucoid inhibitors Chemical MeSH Browser