NADPH Oxidase 2 [NADPH-oxidasa 2]
topical
5
- Terms
-
beta-řetězec cytochromu B-245
NADPH-oxidáza 2
protein CYBB
protein GP91-PHOX
protein NOX2
-
Chronic Granulomatous Disease Protein
CYBB Protein
Cytochrome B-245 Beta Chain
GP91-PHOX Protein
NOX2 Protein
Persistent link
https://www.medvik.cz/link/D000074662
Definition
An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.
- DUI
- D000074662 MeSH Browser
- CUI
- M000627303
- RN
- EC 1.6.3.-
- Previous indexing
- Membrane Glycoproteins (1988-2017); NADPH Oxidases (1997-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 4
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 3
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.682.608.575.750
NADPH Oxidase 1
D12.776.331.894.750
NADPH Oxidase 1
D12.776.543.653.750
NADPH Oxidase 1