Forkhead Box Protein L2 [protein FOXL2]
- Terms
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F-box protein L2
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Forkhead Box L2 Protein
FOXL2 Protein
A forkhead box transcription factor that is expressed in the developing eyelid and during very early development of the gonad, prior to sex determination. It is essential for development of the ovary and inhibits SOX9 TRANSCRIPTION FACTOR to prevent differentiation to testes. It also induces APOPTOSIS in ovarian cells. Mutations in the FOXL2 gene are associated with BLEPHAROPHIMOSIS; Ptosis, and Epicanthus inversus (BPES with ovarian failure).
- DUI
- D000074842 MeSH Browser
- CUI
- M000628267
- Previous indexing
- Forkhead Transcription Factors (2006-2017)
- History note
- 2018
- Public note
- 2018
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- biosynthesis
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- chemistry
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- UL
- ultrastructure
- UR
- urine
FOXL2 protein, human Chemical MeSH Browser
Foxl2 protein, Xenopus Chemical MeSH Browser
Foxl2 protein, mouse Chemical MeSH Browser
foxl2a protein, zebrafish Chemical MeSH Browser