A forkhead box transcription factor and transcriptional activator which triggers type 1 programmed cell death (APOPTOSIS) in the absence of APOPTOSIS INHIBITING PROTEINS, including neuronal cell death induced by OXIDATIVE STRESS. It recognizes and binds to the DNA sequence 5'-(AG)TAAA(TC)A-3' and also functions in post-transcriptional regulation of the c-MYC PROTO-ONCOGENE.

DUI

D000071316 MeSH Prohlížeč

CUI

M000614016

Předchozí užití

Forkhead Transcription Factors (2006-2016)

Historická pozn.

2017

Veřejná pozn.

2017