T-Lymphoma Invasion and Metastasis-inducing Protein 1 [protein TIAM1]
- Terms
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protein TIAM-1
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TIAM-1 Protein
TIAM1 Protein
A Rho guanine nucleotide exchange factor that consists of two pleckstrin homology domains flanking central Ras-binding, Dbl-homology (DH) and PDZ domains. It stimulates GTP-GDP exchange of rho-like GTPases such as RAC1 PROTEIN; CDC42 PROTEIN; and RHOA PROTEIN, and functions to link extracellular signals to remodeling of the CYTOSKELETON for CELL ADHESION and CELL MOVEMENT.
- DUI
- D000075684 MeSH Browser
- CUI
- M000631113
- Previous indexing
- Guanine Nucleotide Exchange Factors (2007-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
TIAM-1 protein, C elegans Chemical MeSH Browser
TIAM1 protein, human Chemical MeSH Browser
Tiam1 protein, mouse Chemical MeSH Browser
Tiam1 protein, rat Chemical MeSH Browser