Angiopoietin-Like Protein 4 [angiopoetinu podobný protein 4]
- Terms
-
angiopoietin-like protein 4
ANGPTL4
-
Angiopoietin-related Protein 4
ANGPTL4 Protein
A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage. ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis.
- DUI
- D000075803 MeSH Browser
- CUI
- M000631469
- Previous indexing
- Angiopoietins (2004-2017); Blood Proteins (2000-2017)
- History note
- 2022(2018)
- Public note
- 2022: see ANGIOPOIETIN-LIKE 4 PROTEIN 2018-2021
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
ANGPTL4 protein, Xenopus Chemical MeSH Browser
ANGPTL4 protein, human Chemical MeSH Browser
ANGPTL4 protein, rat Chemical MeSH Browser
Angptl4 protein, mouse Chemical MeSH Browser
Angptl4 protein, zebrafish Chemical MeSH Browser
peptide fragment cANGPTL4 Chemical MeSH Browser
peptide fragment nANGPTL4 Chemical MeSH Browser