PHD Zinc Fingers [zinkové prsty PHD]

topical
Terms

PHD prst
PHD prsty
PHD-doména
PHD-domény
PHD-motiv
PHD-motivy
PHD-prst
PHD-prsty
zinkový prst PHD

 

PHD Domains
PHD Finger Domain
PHD Fingers
PHD Motif
PHD Motifs
PHD Zinc Finger

Definition

Zinc finger domains of approximately 50 to 80 amino acids in length that are characterized by a conserved Cysteine(3)-Histidine-Cysteine(4) amino acid motif which coordinates binding of two zinc ions. They are similar structurally to RING FINGER DOMAINS, with a globular fold topology of two BETA-SHEETS and an ALPHA-HELIX. PHD fingers occur in many proteins that function in chromatin-mediated gene expression and EPIGENETICS such as POLYCOMB-GROUP PROTEINS.

DUI
D000075925 MeSH Browser
CUI
M000631685
Previous indexing
Amino Acid Sequence (1995-2017); Molecular Sequence Data (1995-2017)
History note
2018
Public note
2018