Phase Variation [fázová variace]

topical
Terms

fázově variabilní regulony

 

Phase-Variable Regulons
Phasevarions

Persistent link   https://www.medvik.cz/link/D000090502
Definition

An adaptive mechanism used by microbes to avoid detection by the host or adapt to changes in environment by randomly and rapidly switch on and off of a gene by various mechanisms between on and off phases. For instance, drug tolerant MYCOBACTERIUM TUBERCULOSIS arises through rapid reversible mutations in the glpK gene through phase variation.

DUI
D000090502 MeSH Browser
CUI
M000746585
History note
2022
Public note
2022

Allowable subheadings

DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G03 Metabolic Phenomena obsolete
G03 Metabolism 1 197
G04 Cell Physiological Phenomena 515
G05 Genetic Phenomena 135
G05.365 Genetic Variation 858
G05.365.036 Antibody Diversity 7
G05.365.073 Antigenic Variation 35
G05.365.331 Genetic Heterogeneity 75
G05.365.461 Heteroplasmy 2
G05.365.590 Mutation 4 997
G05.365.693 Phase Variation
G05.365.795 Polymorphism, Genetic 1 770
G05.365.897 Quasispecies 1
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 17
G12 Immune System Phenomena 249
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 148
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 130
G17 Mathematical Concepts 66

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