Tripeptidyl-Peptidase 1 [tripeptidylpeptidasa 1]
- Terms
-
protein CLN2
protein TPP1
tripeptidylaminopeptidasa I
tripeptidylaminopeptidáza I
tripeptidylpeptidáza 1
tripeptidylpeptidáza I
tripeptidylproteasa 1
tripeptidylproteasa I
tripeptidylproteáza 1
tripeptidylproteáza I
-
CLN2 Protein
TPP1 Protein
Tripeptidyl Aminopeptidase I
Tripeptidyl Peptidase I
Tripeptidyl Protease I
Tripeptidyl-Peptidase I
Lysosomal Serine proteases that release N-terminal tripeptide from a polypeptide and cleave peptides between hydrophobic residues. An enzyme that in humans encoded by the TPP1 gene. It is involved in the degradation of bone collagen. Mutations in this gene are associated with the CEROID LIPOFUSCINOSIS, NEURONAL, 2; and SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE CEROID LIPOFUSCINOSIS, NEURONAL, 2; AND SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 7.
- DUI
- D000091346 MeSH Browser
- CUI
- M000748625
- History note
- 2022 (1993)
- Public note
- 2022; TRIPEPTIDYL-PEPTIDASES 1 was indexed under AMINOPEPTIDASES, DIPEPTIDYL-PEPTIDYL-PEPTIDASES and under SERINE PROTEASES 1995-2021
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
TPP1 protein, human Chemical MeSH Browser
Tpp1 protein, mouse Chemical MeSH Browser
Tpp1 protein, rat Chemical MeSH Browser