Glutathione Peroxidase GPX1 [glutathionperoxidasa (GPx1)]

topical
Terms

glutathionperoxidáza (GPx1)
glutathionperoxidáza 1

 

Glutathione Peroxidase 1
GPX1 Glutathione Peroxidase

Definition

One of the most abundant isoenzymes of the glutathione peroxidase family. Located in the cytosol and mitochondria, it catalyzes the reduction of HYDROGEN PEROXIDE to water, functioning to limit the accumulation of hydrogen peroxide and modulating processes that utilize hydrogen peroxide; and also the reduction of other organic hydroperoxides to their corresponding alcohols.

DUI
D000094765 MeSH Browser
CUI
M0300991
RN
EC 1.11.1.9
History note
2023 (1999)
Public note
2023; was indexed as GLUTATHIONE PEROXIDASE 1999-2021

D Chemicals and Drugs
D08.811 Enzymes 1 547
D08.811.682 Oxidoreductases 446
D08.811.682.732 Peroxidases 207
D08.811.682.732.500 Glutathione Peroxidase 220
D08.811.682.732.500.500 Glutathione Peroxidase GPX1
D12.776 Proteins 2 575
D12.776.864 Selenoproteins 12
D12.776.864.050 Glutathione Peroxidase 220
D12.776.864.050.500 Glutathione Peroxidase GPX1