Neurexins [neurexiny]

topical
Persistent link   https://www.medvik.cz/link/D000096784
Definition

Presynaptic cell-adhesion molecules that bind postsynaptic NEUROLIGINS to form calcium-dependent trans-synaptic adhesions. Neurexins recruit synaptic scaffolding proteins via their PDZ DOMAINS. Distribution and interaction with neuroligins are regulated by ALTERNATIVE SPLICING. Alterations in genes encoding neurexins are associated with cognitive diseases such AUTISM SPECTRUM DISORDER; SCHIZOPHRENIA and Pitt-Hopkins-like syndrome 2.

DUI
D000096784 MeSH Browser
CUI
M000762630
Previous indexing
Nerve Tissue Proteins (1992-2023)
History note
2024
Public note
2024

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D09 Carbohydrates 723
D09.400 Glycoconjugates 58
D09.400.430 Glycoproteins 637
D09.400.430.890 Membrane Glycoproteins 200
D09.400.430.890.200 Cell Adhesion Molecules 309
D09.400.430.890.200.250 Cell Adhesion Molecules, Neuronal 9
D09.400.430.890.200.250.150 Cell Adhesion Molecules, Neuron-Glia 1
D09.400.430.890.200.250.325 Contactins 2
D09.400.430.890.200.250.500 Myelin P0 Protein 8
D09.400.430.890.200.250.520 Neural Cell Adhesion Molecules 9
D09.400.430.890.200.250.640 Neurexins
D09.400.430.890.200.250.760 Reelin Protein
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.395 Glycoproteins 637
D12.776.395.550 Membrane Glycoproteins 200
D12.776.395.550.200 Cell Adhesion Molecules 309
D12.776.395.550.200.250 Cell Adhesion Molecules, Neuronal 9
D12.776.395.550.200.250.150 Cell Adhesion Molecules, Neuron-Glia 1
D12.776.395.550.200.250.325 Contactins 2
D12.776.395.550.200.250.500 Myelin P0 Protein 8
D12.776.395.550.200.250.520 Neural Cell Adhesion Molecules 9
D12.776.395.550.200.250.640 Neurexins
D12.776.395.550.200.250.760 Reelin Protein
D12.776.543 Membrane Proteins 849
D12.776.543.550 Membrane Glycoproteins 200
D12.776.543.550.200 Cell Adhesion Molecules 309
D12.776.543.550.200.250 Cell Adhesion Molecules, Neuronal 9
D12.776.543.550.200.250.150 Cell Adhesion Molecules, Neuron-Glia 1
D12.776.543.550.200.250.325 Contactins 2
D12.776.543.550.200.250.500 Myelin P0 Protein 8
D12.776.543.550.200.250.520 Neural Cell Adhesion Molecules 9
D12.776.543.550.200.250.760 Neurexins
D12.776.631 Nerve Tissue Proteins 263
D12.776.631.024 Acid Sensing Ion Channels 2
D12.776.631.050 Agrin
D12.776.631.069 Ataxins 2
D12.776.631.087 Calbindin 1
D12.776.631.124 Chimerin Proteins 2
D12.776.631.199 Chromogranins 25
D12.776.631.212 Collapsin Response Mediator Protein 1
D12.776.631.224 Disks Large Homolog 4 Protein 1
D12.776.631.249 Dopamine and cAMP-Regulated Phosphoprotein 32 3
D12.776.631.262 Dysbindin
D12.776.631.274 Fatty Acid-Binding Protein 7 1
D12.776.631.299 Fragile X Mental Retardation Protein 7
D12.776.631.400 GAP-43 Protein 5
D12.776.631.480 Glucose Transporter Type 3
D12.776.631.520 ELAV Proteins 2
D12.776.631.530 Homeobox Protein SIX3
D12.776.631.540 Metallothionein 3 1
D12.776.631.560 Microtubule-Associated Proteins 101
D12.776.631.580 Myelin Proteins 32
D12.776.631.590 Natriuretic Peptide, Brain 347
D12.776.631.600 Nerve Growth Factors 70
D12.776.631.607 Nestin 17
D12.776.631.609 Neurexins
D12.776.631.611 Neuro-Oncological Ventral Antigen
D12.776.631.615 Neuroendocrine Secretory Protein 7B2
D12.776.631.630 Neurofilament Proteins 51
D12.776.631.635 Neuroglobin
D12.776.631.640 Neurogranin 1
D12.776.631.641 Neuroligins
D12.776.631.642 Neuronal Apoptosis-Inhibitory Protein
D12.776.631.645 Neuronal Calcium-Sensor Proteins 1
D12.776.631.650 Neuropeptides 202
D12.776.631.651 Nogo Receptors
D12.776.631.653 Olfactory Marker Protein
D12.776.631.654 Oligodendrocyte Transcription Factor 2
D12.776.631.656 Rabphilin-3A
D12.776.631.658 S100 Proteins 133
D12.776.631.703 SAP90-PSD95 Associated Proteins
D12.776.631.727 Slit Homolog 2 Protein
D12.776.631.750 Synapsins 2
D12.776.631.775 Synaptogyrins 1
D12.776.631.800 Synaptophysin 10
D12.776.631.860 Synucleins 3
D12.776.631.920 Tubulin 160
D12.776.631.960 Voltage-Gated Sodium Channels 6
D23 Biological Factors 143
D23.050 Antigens 1 131
D23.050.301 Antigens, Surface 171
D23.050.301.350 Cell Adhesion Molecules 309
D23.050.301.350.250 Cell Adhesion Molecules, Neuronal 9
D23.050.301.350.250.150 Cell Adhesion Molecules, Neuron-Glia 1
D23.050.301.350.250.325 Contactins 2
D23.050.301.350.250.500 Myelin P0 Protein 8
D23.050.301.350.250.520 Neural Cell Adhesion Molecules 9
D23.050.301.350.250.760 Neurexins

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