Antimetabolites [antimetabolity]

topical
120
Terms

Antimetabolite

Persistent link   https://www.medvik.cz/link/D000963
Definition

Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (From AMA Drug Evaluations Annual, 1994, p2033)

DUI
D000963 MeSH Browser
CUI
M0001470

Allowable subheadings

AD
administration & dosage 14
AE
adverse effects 11
AN
analysis 0
BL
blood 1
CF
cerebrospinal fluid 0
CS
chemical synthesis 1
CH
chemistry 1
CL
classification 1
EC
economics 0
HI
history 0
IM
immunology 0
IP
isolation & purification 0
ME
metabolism 7
PK
pharmacokinetics 4
PD
pharmacology 30
PO
poisoning 0
RE
radiation effects 1
ST
standards 0
SD
supply & distribution 0
TU
therapeutic use 41
TO
toxicity 4
UR
urine 1

D Chemicals and Drugs
D27 Chemical Actions and Uses 374
D27.505 Pharmacologic Actions 408
D27.505.519 Molecular Mechanisms of Pharmacological Action 89
D27.505.519.124 Alkylating Agents 91
D27.505.519.143 Amylin Receptor Agonists
D27.505.519.162 Angiotensin Receptor Antagonists 222
D27.505.519.170 Antacids 162
D27.505.519.174 Antidiuretic Hormone Receptor Antagonists 28
D27.505.519.178 Antifoaming Agents 12
D27.505.519.182 Antiglycation Agents
D27.505.519.186 Antimetabolites 120
D27.505.519.186.071 Hypolipidemic Agents 1 622
D27.505.519.186.144 Antimetabolites, Antineoplastic 189
D27.505.519.217 Antioxidants 2 518
D27.505.519.241 Aversive Agents
D27.505.519.265 Bradykinin Receptor Antagonists 10
D27.505.519.270 Calcitonin Gene-Related Peptide Receptor Antagonists 72
D27.505.519.275 CCR5 Receptor Antagonists 4
D27.505.519.295 Cerumenolytic Agents 1
D27.505.519.334 Cystine Depleting Agents
D27.505.519.349 Cytochrome P-450 Enzyme Inducers 10
D27.505.519.364 Endothelin Receptor Antagonists 119
D27.505.519.374 Enzyme Activators 30
D27.505.519.389 Enzyme Inhibitors 873
D27.505.519.405 Enzyme Reactivators 16
D27.505.519.421 Fibrin Modulating Agents 2
D27.505.519.452 Heparin Antagonists 23
D27.505.519.507 Immune Checkpoint Inhibitors 319
D27.505.519.562 Membrane Transport Modulators 22
D27.505.519.593 Mitosis Modulators 3
D27.505.519.625 Neurotransmitter Agents 517
D27.505.519.656 Nitric Oxide Donors 63
D27.505.519.828 Peptidomimetics 11
D27.505.519.871 Radiopharmaceuticals 806
D27.505.519.914 Sequestering Agents 1
D27.505.519.936 Sodium-Glucose Transporter 2 Inhibitors 780
D27.505.519.947 Sphingosine 1 Phosphate Receptor Modulators 25
D27.505.519.952 Toll-Like Receptor Agonists
D27.505.519.957 Viral Fusion Protein Inhibitors
D27.888 Toxic Actions 158
D27.888.569 Noxae 112
D27.888.569.035 Alkylating Agents 91
D27.888.569.042 Antimetabolites 120
D27.888.569.042.030 Antimetabolites, Antineoplastic 189
D27.888.569.071 Antispermatogenic Agents 18
D27.888.569.100 Carcinogens 1 021
D27.888.569.142 Cardiotoxins 28
D27.888.569.185 Caustics 32
D27.888.569.199 Cytostatic Agents 460
D27.888.569.213 Cytotoxins 130
D27.888.569.242 Dermotoxins 2
D27.888.569.279 Immunotoxins 57
D27.888.569.300 Irritants 74
D27.888.569.468 Mutagens 833
D27.888.569.504 Neurotoxins 172
D27.888.569.540 Oxidants 78
D27.888.569.612 Poisons 290
D27.888.569.673 Pyrogens 72
D27.888.569.734 Riot Control Agents, Chemical 2
D27.888.569.864 Teratogens 484

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