A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.

DUI

D002373 MeSH Browser

CUI

M0003612

Previous indexing

Amino Acid Sequence (1975-1987); Bacterial Proteins (1972-1987); Base Sequence (1980-1987); Receptors, Cyclic AMP (1980-1993); Transcription Factors (1980-1987); Transcription, Genetic (1978-1987)

History note

94; was CATABOLITE GENE ACTIVATOR PROTEINS 1988-93; CYCLIC AMP RECEPTOR PROTEIN was see CATABOLITE GENE ACTIVATOR PROTEIN 1990-93; CATABOLITE GENE ACTIVATOR PROTEIN was see RECEPTORS, CYCLIC AMP 1987; CATABOLITE ACTIVATOR PROTEIN was see RECEPTORS, CYCLIC AMP 1987; CATABOLIC GENE ACTIVATORS was see RECEPTORS, CYCLIC AMP 1977-87

Online note

use CYCLIC AMP RECEPTOR PROTEIN to search CATABOLITE GENE ACTIVATOR PROTEINS 1988-93; use RECEPTORS, CYCLIC AMP to search CATABOLITE GENE ACTIVATOR PROTEINS & CATABOLITE ACTIVATOR PROTEIN 1987 & CATABOLIC GENE ACTIVATORS 1977-87

Public note

94; was CATABOLITE GENE ACTIVATOR PROTEINS 1988-93; CYCLIC AMP RECEPTOR PROTEIN was see CATABOLITE GENE ACTIVATOR PROTEIN 1990-93; CATABOLITE GENE ACTIVATOR PROTEIN was see RECEPTORS, CYCLIC AMP 1987; CATABOLITE ACTIVATOR PROTEIN was see RECEPTORS, CYCLIC AMP 1987; CATABOLIC GENE ACTIVATORS was see RECEPTORS, CYCLIC AMP 1977-87