Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.

Annotation

do not routinely add when indexing coagulase negative organisms; index only when discussed

DUI

D003030 MeSH Browser

CUI

M0004656

History note

66(64); was see under HYDROLASES 1963-65; STAPHYLOCOAGULASE was see under HYDROLASES 1963-67

Online note

use HYDROLASES to search STAPHYLOCOAGULASE 1966-67

Public note

66; was see under HYDROLASES 1963-65; STAPHYLOCOAGULASE was see under HYDROLASES 1963-67