The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb), and COMPLEMENT C5 CONVERTASES in both the classical (C4b2a3b) and the alternative (C3bBb3b) pathway. C3b participates in IMMUNE ADHERENCE REACTION and enhances PHAGOCYTOSIS. It can be inactivated (iC3b) or cleaved by various proteases to yield fragments such as COMPLEMENT C3C; COMPLEMENT C3D; C3e; C3f; and C3g.

Anotace

/antag: consider COMPLEMENT C3B INACTIVATOR PROTEINS

DUI

D003179 MeSH Prohlížeč

CUI

M0004932

CAS

Complement C3b

Předchozí užití

Complement (1968-1974); Complement 3 (1975-1977)

Historická pozn.

2006 (1978)

Veřejná pozn.

2006; see COMPLEMENT 3B 1978-2005