Dextromethorphan [dextromethorfan]
- Terms
-
d-Methorphan
Delsym
Dextromethorphan Hydrobromide
Dextromethorphan Hydrobromide, (+-)-Isomer
Dextromethorphan Hydrobromide, Monohydrate
Dextromethorphan Hydrochloride
Dextromethorphan, (+-)-Isomer
Racemethorphan
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
- DUI
- D003915 MeSH Browser
- CUI
- M0006138
- CAS
- Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-
- Previous indexing
- Morphinans (1969-1971); Antitussive Agents (1966-1971)
- History note
- 91(72); was see under LEVORPHANOL 1972-90
- Public note
- 91; was see under LEVORPHANOL 1972-90
Allowable subheadings
- AD
- administration & dosage 13
- AE
- adverse effects 15
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis 4
- AI
- antagonists & inhibitors
- BL
- blood 2
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 4
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification 1
- ME
- metabolism 12
- PK
- pharmacokinetics 11
- PD
- pharmacology 12
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 15
- TO
- toxicity
- UR
- urine 4
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