Digoxin [digoxin]
- Terms
-
Digoxin
-
Digacin
Digitek
Digoregen
Digoxina Boehringer
Digoxine Nativelle
Dilanacin
Hemigoxine Nativelle
Lanacordin
Lanicor
Lanoxicaps
Lanoxin
Lanoxin-PG
Lenoxin
Mapluxin
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
- Annotation
- do not confuse with DIGITOXIN
- nepleť s deskriptorem DIGITOXIN
- DUI
- D004077 MeSH Browser
- CUI
- M0006386
- RN
- 73K4184T59
- CAS
- Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-
Allowable subheadings
- AD
- administration & dosage 77
- AE
- adverse effects 41
- AG
- agonists 0
- AA
- analogs & derivatives 9
- AN
- analysis 17
- AI
- antagonists & inhibitors 2
- BL
- blood 42
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 3
- CH
- chemistry 5
- CL
- classification 0
- EC
- economics 1
- HI
- history 0
- IM
- immunology 7
- IP
- isolation & purification 0
- ME
- metabolism 10
- PK
- pharmacokinetics 15
- PD
- pharmacology 39
- PO
- poisoning 6
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 125
- TO
- toxicity 13
- UR
- urine 5