DNA, Satellite [satelitní DNA]
- Terms
-
DNA satelitní
satDNA
satelitní DNA I
satelitní DNA typu I
satelitní DNA, typ I
-
Satellite DNA
Satellite I DNA
Highly repetitive DNA sequences found in HETEROCHROMATIN, mainly near centromeres. They are composed of simple sequences (very short) (see MINISATELLITE REPEATS) repeated in tandem many times to form large blocks of sequence. Additionally, following the accumulation of mutations, these blocks of repeats have been repeated in tandem themselves. The degree of repetition is on the order of 1000 to 10 million at each locus. Loci are few, usually one or two per chromosome. They were called satellites since in density gradients, they often sediment as distinct, satellite bands separate from the bulk of genomic DNA owing to a distinct BASE COMPOSITION.
- DUI
- D004276 MeSH Browser
- CUI
- M0006691
- Previous indexing
- DNA (1966-1974)
- History note
- 80(75); was see under DNA 1975-79
- Public note
- 80; was see under DNA 1975-79
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 7
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 3
- CL
- classification 1
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 32
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 2
- ME
- metabolism 1
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0