Colforsin [kolforsin]

topical
23
Terms

forskolin

 

Coleonol
Forskolin
N,N-Dimethyl-beta-alanine-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl Ester HCl
NKH 477
NKH-477
NKH477

Persistent link   https://www.medvik.cz/link/D005576
Definition

Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant COLEUS FORSKOHLII. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.

DUI
D005576 MeSH Browser
CUI
M0358301
CAS
1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-
Previous indexing
Terpenes (1966-1973); Diterpenes (1974-1985)
History note
2014(1986)
Public note
2014; see FORSKOLIN 1986-2013

D Chemicals and Drugs
D02.455 Hydrocarbons 139
D02.455.849 Terpenes 139
D02.455.849.291 Diterpenes 51
D02.455.849.291.040 Abietanes 7
D02.455.849.291.075 Aphidicolin 2
D02.455.849.291.162 Atractyloside 2
D02.455.849.291.184 Diterpene Alkaloids
D02.455.849.291.300 Colforsin 23
D02.455.849.291.325 Diterpenes, Clerodane 4
D02.455.849.291.350 Diterpenes, Kaurane 10
D02.455.849.291.400 Ginkgolides 9
D02.455.849.291.500 Phorbols 12
D02.455.849.291.515 Phytanic Acid 1
D02.455.849.291.523 Phytol 1
D02.455.849.291.564 Pleuromutilins
D02.455.849.291.605 Retinaldehyde 5
D02.455.849.291.686 Ryanodine 17
D02.455.849.291.850 Taxoids 389
D02.455.849.291.925 Vitamin A 406
D10 Lipids 2 528