Immunoglobulin Idiotypes [idiotypy]
topical
10
- Terms
-
idiotypy imunoglobulinů
imunoglobulinové idiotypy
-
Idiotypes, Immunoglobulin
Ig Idiotypes
Persistent link
https://www.medvik.cz/link/D007130
Definition
Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
- DUI
- D007130 MeSH Browser
- CUI
- M0011109
- Previous indexing
- Antigenic Determinants (1970-1978); Binding Sites, Antibody (1973-1978); Anti-Antibodies (1966-1969); Antibody Specificity (1970-1978)
- History note
- 79
- Public note
- 79
Allowable subheadings
- AD
- administration & dosage 1
- AE
- adverse effects
- AN
- analysis
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CH
- chemistry
- CL
- classification
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology 4
- IP
- isolation & purification 1
- ME
- metabolism
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- TU
- therapeutic use 2
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
anti-GAT antibodies, idiotypic Chemical MeSH Browser