Immunoglobulin Switch Region [přesmyková sekvence imunoglobulinů]

topical
Terms

oblasti přesmyku Ig
přesmyková sekvence těžkého řetězce mu

 

Heavy-Chain Mu Switch Region
Ig Switch Region
Ig Switch Sequences
Switch Region, Immunoglobulin

Persistent link   https://www.medvik.cz/link/D007134
Definition

A site located in the INTRONS at the 5' end of each constant region segment of a immunoglobulin heavy-chain gene where recombination (or rearrangement) occur during IMMUNOGLOBULIN CLASS SWITCHING. Ig switch regions are found on genes encoding all five classes (IMMUNOGLOBULIN ISOTYPES) of IMMUNOGLOBULIN HEAVY CHAINS.

DUI
D007134 MeSH Browser
CUI
M0011115
Previous indexing
Immunoglobulin Constant Region (1979-1987); Immunoglobulin Variable Region (1977-1987); Genes, Structural (1977-1987)
History note
88
Public note
88

Allowable subheadings

DE
drug effects
ES
ethics
GE
genetics
IM
immunology
IP
isolation & purification
PH
physiology
RE
radiation effects

G Phenomena and Processes
G05 Genetic Phenomena 135
G05.360 Genetic Structures 25
G05.360.340 Genome 361
G05.360.340.024 Genome Components 13
G05.360.340.024.340 Genes 673
G05.360.340.024.340.137 Gene Components 6
G05.360.340.024.340.137.190 Codon 81
G05.360.340.024.340.137.232 Exons 261
G05.360.340.024.340.137.275 Expressed Sequence Tags 13
G05.360.340.024.340.137.290 3' Flanking Region 3
G05.360.340.024.340.137.295 5' Flanking Region 5
G05.360.340.024.340.137.430 Immunoglobulin Switch Region
G05.360.340.024.340.137.515 Introns 116
G05.360.340.024.340.137.650 Open Reading Frames 128
G05.360.340.024.340.137.750 Regulatory Elements, Transcriptional 3
G05.360.340.024.340.137.775 RNA 3' Polyadenylation Signals
G05.360.340.024.340.137.785 RNA 5' Terminal Oligopyrimidine Sequence
G05.360.340.024.340.137.800 RNA Splice Sites 35
G05.360.340.024.340.137.910 Untranslated Regions 5
G05.360.340.024.340.335 Genes, Immunoglobulin 41
G05.360.340.024.340.335.300 Genes, Immunoglobulin Heavy Chain 20
G05.360.340.024.340.335.300.249 Hinge Exons
G05.360.340.024.340.335.300.500 Immunoglobulin Switch Region

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