Metabolic Clearance Rate [metabolická clearance]

topical
224
Terms

totální clearance

 

Total Body Clearance Rate

Persistent link   https://www.medvik.cz/link/D008657
Definition

Volume of biological fluid completely cleared of drug metabolites as measured in unit time. Elimination occurs as a result of metabolic processes in the kidney, liver, saliva, sweat, intestine, heart, brain, or other site.

Annotation
NIM with specific drug /pharmacokin (IM); not for metabolic rate: read restricted MeSH definition
DUI
D008657 MeSH Browser
CUI
M0013490
Previous indexing
specific heading/metabolism (1966-1967)
History note
68
Public note
68

Allowable subheadings

DE
drug effects 21
GE
genetics
IM
immunology 1
PH
physiology 16
RE
radiation effects

E Analytical, Diagnostic and Therapeutic Techniques and Equipment
E01 Diagnosis 1 794
E01.370 Diagnostic Techniques and Procedures 3 433
E01.370.225 Clinical Laboratory Techniques 6 398
E01.370.225.124 Clinical Chemistry Tests 251
E01.370.225.312 COVID-19 Testing 143
E01.370.225.500 Cytological Techniques 566
E01.370.225.562 Genetic Testing 1 312
E01.370.225.625 Hematologic Tests 495
E01.370.225.750 Histological Techniques 1 403
E01.370.225.812 Immunologic Tests 1 250
E01.370.225.828 Laboratory Critical Values 21
E01.370.225.843 Metabolic Clearance Rate 224
E01.370.225.875 Microbiological Techniques 1 423
E01.370.225.880 Molecular Diagnostic Techniques 1 041
E01.370.225.910 Neonatal Screening 545
E01.370.225.925 Occult Blood 256
E01.370.225.932 Parasite Load 24
E01.370.225.940 Parasitic Sensitivity Tests 18
E01.370.225.948 Pooled Testing
E01.370.225.955 Pre-Analytical Phase 21
E01.370.225.970 Pregnancy Tests 121
E01.370.225.985 Radioligand Assay 30
E01.370.225.989 Rapid Diagnostic Tests 1
E01.370.225.992 Semen Analysis 102
E01.370.225.996 Sex Determination Analysis 43
E01.370.225.998 Specimen Handling 1 032
E05 Investigative Techniques 210
E05.200 Clinical Laboratory Techniques 6 398
E05.200.124 Clinical Chemistry Tests 251
E05.200.312 COVID-19 Testing 143
E05.200.500 Cytological Techniques 566
E05.200.562 Genetic Testing 1 312
E05.200.625 Hematologic Tests 495
E05.200.750 Histological Techniques 1 403
E05.200.812 Immunologic Tests 1 250
E05.200.828 Laboratory Critical Values 21
E05.200.843 Metabolic Clearance Rate 224
E05.200.875 Microbiological Techniques 1 423
E05.200.880 Molecular Diagnostic Techniques 1 041
E05.200.910 Neonatal Screening 545
E05.200.925 Occult Blood 256
E05.200.932 Parasite Load 24
E05.200.940 Parasitic Sensitivity Tests 18
E05.200.970 Pregnancy Tests 121
E05.200.985 Radioligand Assay 30
E05.200.989 Rapid Diagnostic Tests 1
E05.200.992 Semen Analysis 102
E05.200.996 Sex Determination Analysis 43
E05.200.998 Specimen Handling 1 032

G Phenomena and Processes
G03 Metabolism 1 203
G03 Metabolic Phenomena obsolete
G03.015 Absorption 273
G03.030 Acid-Base Equilibrium 446
G03.040 Acylation 24
G03.049 Aerobiosis 73
G03.059 Alkylation 65
G03.068 Amination 7
G03.078 Anaerobiosis 143
G03.087 Autotrophic Processes 13
G03.105 Biocatalysis 83
G03.143 Biological Transport 887
G03.162 Biotinylation 20
G03.171 Biotransformation 798
G03.180 Body Composition 548
G03.185 Brain Chemistry 424
G03.191 Carbohydrate Metabolism 493
G03.194 Catabolite Repression 2
G03.197 Cell Respiration 106
G03.208 Cyclization 55
G03.219 Dealkylation 4
G03.222 Deamination 10
G03.225 Decarboxylation 17
G03.230 Dimerization 102
G03.295 Energy Metabolism 1 589
G03.312 Enterohepatic Circulation 7
G03.328 Enzyme Activation 380
G03.344 Esterification 62
G03.360 Halogenation 45
G03.393 Heterotrophic Processes 20
G03.409 Hydrogenation 24
G03.425 Hydroxylation 65
G03.442 Insulin Secretion 26
G03.458 Lipid Metabolism 1 403
G03.474 Melanogenesis
G03.490 Metabolic Clearance Rate 224
G03.493 Metabolic Networks and Pathways 148
G03.500 Metabolome 140
G03.558 Nitrosation 12
G03.615 Osmoregulation 11
G03.673 Oxidative Stress 2 145
G03.680 Oxygen Consumption 1 195
G03.707 Oxygen Saturation 23
G03.734 Peptide Biosynthesis 43
G03.787 Pharmacokinetics 758
G03.796 Phosphorylation 724
G03.800 Phototrophic Processes 25
G03.804 Prenylation 15
G03.808 Protein Binding 1 259
G03.812 Proteolysis 131
G03.816 Proteostasis 8
G03.818 Proteotoxic Stress
G03.820 Renin-Angiotensin System 683
G03.839 RNA Processing, Post-Transcriptional 57
G03.857 Secretory Rate 28
G03.893 Toxicokinetics 8
G07 Physiological Phenomena 176
G07.690 Pharmacological and Toxicological Phenomena 59
G07.690.595 Metabolic Clearance Rate 224
G07.690.725 Pharmacokinetics 758
G07.690.725.015 Absorption 273
G07.690.725.064 Area Under Curve 171
G07.690.725.129 Biological Availability 290
G07.690.725.225 Biotransformation 798
G07.690.725.249 Chronopharmacokinetics
G07.690.725.297 Drug Elimination Routes 7
G07.690.725.321 Drug Liberation 167
G07.690.725.513 Metabolic Clearance Rate 224
G07.690.725.898 Therapeutic Equivalency 174
G07.690.725.949 Tissue Distribution 272
G07.690.773 Pharmacological Phenomena 46
G07.690.812 Pharmacological Processes obsolete
G07.690.915 Toxicokinetics 8
G07.690.936 Toxicological Phenomena 5

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