Methimazole [methimazol]
- Terms
-
1-Methyl-2-mercaptoimidazole
Favistan
Mercasolyl
Mercazol
Mercazole
Mercazolyl
Merkazolil
Methizol
Methylmercaptoimidazole
Methymazol
Metisol
Metizol
Strumazol
Tapazole
Thiamazol Henning
Thiamazol Hexal
Thiamazole
Thimazol
Thyrozol
Tiamazol
Tirodril
A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
- DUI
- D008713 MeSH Browser
- CUI
- M0013573
- RN
- 554Z48XN5E
- CAS
- 2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-
- Previous indexing
- Imidazoles (1966-1967); Thyroid Antagonists (1966-1967)
- History note
- 73(68); was see under THYROID ANTAGONISTS 1963-72
- Online note
- search THYROID ANTAGONISTS 1966-67
- Public note
- 73; was see under THYROID ANTAGONISTS 1963-72
Allowable subheadings
- AD
- administration & dosage 29
- AE
- adverse effects 14
- AG
- agonists 0
- AA
- analogs & derivatives 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 1
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 1
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 0
- PD
- pharmacology 5
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 30
- TO
- toxicity 1
- UR
- urine 0