Mercaptopurine [merkaptopurin]
- Terms
-
6-merkaptopurin
arabinosyl-6-merkaptopurin
Puri-nethol
-
1,7-Dihydro-6H-purine-6-thione
6-Mercaptopurine
6-Mercaptopurine Monohydrate
6-Thiohypoxanthine
6-Thiopurine
6H-Purine-6-thione, 1,7-dihydro-
BW 57-323H
Leupurin
Mecaptopurine Anhydrous
Mercaptopurina Wellcome
Puri-Nethol
Purimethol
Purinethol
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
- DUI
- D015122 MeSH Browser
- CUI
- M0023263
- History note
- 2018(1985)
- Public note
- 2018; see 6-Mecaptopurine 1985-2017; see MERCAPTOPURINE 1963-1984; see ARABINOSYL-6-MERCAPTOPURINE 1975-1991; MERCAPTOPURINE was indexed under 6-MERCAPTOPURINE 1975-1990
Allowable subheadings
- AD
- administration & dosage 16
- AE
- adverse effects 14
- AG
- agonists
- AA
- analogs & derivatives 14
- AN
- analysis 4
- AI
- antagonists & inhibitors
- BL
- blood 3
- CF
- cerebrospinal fluid
- CS
- chemical synthesis 1
- CH
- chemistry 4
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology 4
- IP
- isolation & purification 2
- ME
- metabolism 11
- PK
- pharmacokinetics 4
- PD
- pharmacology 24
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 33
- TO
- toxicity 3
- UR
- urine 1