A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin is also used to reduce hypercalcemia, especially that due to malignancies.

DUI

D008926 MeSH Prohlížeč

CUI

M0013935

CAS

Mithramycin

Předchozí užití

Antibiotics, Antineoplastic (1967-1970)

Historická pozn.

93; was MITHRAMYCIN 1971-92 (Prov 1971-72)

Online pozn.

use PLICAMYCIN to search MITHRAMYCIN 1971-92 (as Prov 1971-72)

Veřejná pozn.

93; was MITHRAMYCIN 1973-92