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Plicamycin [mithramycin]
topical
3
- Terms
-
Aureolic Acid
Mithramycin
Mitramycin
Persistent link
https://www.medvik.cz/link/D008926
Definition
A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin is also used to reduce hypercalcemia, especially that due to malignancies.
- DUI
- D008926 MeSH Browser
- CUI
- M0013935
- CAS
- Mithramycin
- Previous indexing
- Antibiotics, Antineoplastic (1967-1970)
- History note
- 93; was MITHRAMYCIN 1971-92 (Prov 1971-72)
- Online note
- use PLICAMYCIN to search MITHRAMYCIN 1971-92 (as Prov 1971-72)
- Public note
- 93; was MITHRAMYCIN 1973-92
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives 1
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D02.455.426.559.847.562.050.825
Pradimicins and Benanomicins
D04.615.562.050.825
Pradimicins and Benanomicins
D09.408.051.059.825
Pradimicins and Benanomicins