A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).

DUI

D009840 MeSH Browser

CUI

M0015277

History note

82; was OLIGOMYCIN 1963-81 (Prov 1963-65)

Online note

use OLIGOMYCINS to search OLIGOMYCIN 1966-81

Public note

82; was OLIGOMYCIN 1966-81; RUTAMYCIN was see under ANTIBIOTICS, ANTIFUNGAL 1975-81