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Thymidylate Synthase [thymidylátsynthasa]
topical
43
- Terms
-
thymidylátsyntáza
thymidylátsyntetáza
tymidylátsyntáza
tymidylátsyntetáza
-
Thymidylate Synthetase
Persistent link
https://www.medvik.cz/link/D013940
Definition
An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.
- DUI
- D013940 MeSH Browser
- CUI
- M0021454
- CAS
- 5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase
- Previous indexing
- Ligases (1966-1970); Methyltransferases (1971-1972); Transferases (1969-1972)
- History note
- 1998; see METHYLTRANSFERASES 1975-1985
- Public note
- 1998; see METHYLTRANSFERASES 1975-1985, see THYMIDYLATE SYNTHETASE 1985-1997
Allowable subheadings
- AD
- administration & dosage 3
- AE
- adverse effects 1
- AN
- analysis 3
- AI
- antagonists & inhibitors 17
- BI
- biosynthesis
- BL
- blood 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects 2
- EC
- economics
- GE
- genetics 9
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 4
- PK
- pharmacokinetics 2
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 12
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.913.555
One-Carbon Group Transferases
D08.811.913.555.500.625
Homocysteine S-Methyltransferase
D08.811.913.555.500.710
Phosphatidyl-N-Methylethanolamine N-Methyltransferase
TYMS protein, human Chemical MeSH Browser
deoxycytidylate methylase Chemical MeSH Browser
thymidylate synthase-dihydrofolate reductase Chemical MeSH Browser