N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.

DUI

D014405 MeSH Browser

CUI

M0022144

CAS

L-Arginine, N2-(1-(N2-L-threonyl-L-lysyl)-L-prolyl)-

Previous indexing

Oligopeptides (1973-1974); Immunoglobulin Fragments (1973-1974)

History note

84(75); was see under IMMUNOGLOBULINS, FD 1975-83; LEUKOKININ (with LEUCOKININ a see ref to it) was see under GAMMA GLOBULINS 1975-83; LEUKOKININ & LEUCOKININ were see TUFTSIN 1984-93

Online note

use TUFTSIN to search LEUKOKININ & LEUCOKININ 1975-93

Public note

84; was see under IMMUNOGLOBULINS, FD 1975-83; LEUKOKININ (with LEUCOKININ a see ref to it) was see under GAMMA GLOBULINS 1975-83; LEUKOKININ & LEUCOKININ were see TUFTSIN 1984-93