Uroporphyrinogen III Synthetase [uroporfyrinogen-III-synthetasa]
topical
1
- Terms
-
kosyntáza
kosynthasa
uroporfyrinogen-III-kosyntáza
uroporfyrinogen-III-kosyntetáza
uroporfyrinogen-III-kosynthetasa
uroporfyrinogen-III-syntáza
uroporfyrinogen-III-syntetáza
uroporfyrinogen-III-synthasa
uroporfyrinogenisomerasa
-
Cosynthase
Uroporphyrinogen III Cosynthetase
Uroporphyrinogen Isomerase
Uroporphyrinogen-III Synthase
Persistent link
https://www.medvik.cz/link/D014576
Definition
An enzyme that catalyzes the cyclization of hydroxymethylbilane to yield UROPORPHYRINOGEN III and water. It is the fourth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by UROS gene. Mutations of UROS gene result in CONGENITAL ERYTHROPOIETIC PORPHYRIA.
- DUI
- D014576 MeSH Browser
- CUI
- M0022407
- CAS
- Hydroxymethylbilane hydro-lyase (cyclizing)
- Previous indexing
- Porphobilinogen (1973-1974); Isomerases (1971-1974)
- History note
- 2005 (1975)
- Public note
- 2005; see UROPORPHYRINOGEN-III SYNTHASE 1998-2004, see UROPORPHYRINOGEN III SYNTHASE 1991-1997, see HYDRO-LYASES 1985-1990, see ISOMERASES 1975-1984
Combination
- deficiency
- Porphyria, Erythropoietic
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.520.241.300.275
Enoyl-CoA Hydratase 2
D08.811.520.241.300.600
Prephenate Dehydratase
D08.811.520.241.300.650
Propanediol Dehydratase
D08.811.520.241.300.900
Urocanate Hydratase