Nedostatek vitaminu E v potravě se projevuje abnormalitami v oblasti zadních provazců míšních a spinocerebelárních traktů, areflexií, oftalmoplegií, poruchami chůze a propriocepce a třesem. U nedonošených kojenců tento deficit souvisí s hemolytickou anemií, trombocytózou, otoky, intraventrikulární hemoragií a zvýšeným rizikem retinopatie a bronchopulmonální dysplazie. Byla objevena vrozená porucha metabolismu vitaminu E.

A nutritional condition produced by a deficiency of VITAMIN E in the diet, characterized by posterior column and spinocerebellar tract abnormalities, areflexia, ophthalmoplegia, and disturbances of gait, proprioception, and vibration. In premature infants vitamin E deficiency is associated with hemolytic anemia, thrombocytosis, edema, intraventricular hemorrhage, and increasing risk of retrolental fibroplasia and bronchopulmonary dysplasia. An apparent inborn error of vitamin E metabolism, named familial isolated vitamin E deficiency, has recently been identified. (Cecil Textbook of Medicine, 19th ed, p1181)

DUI

D014811 MeSH Prohlížeč

CUI

M0022804