Cytochrome P-450 CYP2D6 [cytochrom P-450 CYP2D6]
topical
119
- Terms
-
CYP 2D6
CYP2D6
cytochrom P450 2D6
debrisochinhydroxyláza
-
CYP 2D6
CYP2D6
Cytochrome P450 2D6
Debrisoquine 4-Hydroxylase
Debrisoquine 4-Monooxygenase
Debrisoquine Hydroxylase
Imipramine 2-Hydroxylase
Sparteine Monooxygenase
Persistent link
https://www.medvik.cz/link/D019389
Definition
A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.
- DUI
- D019389 MeSH Browser
- CUI
- M0028855
- Previous indexing
- Cytochrome P-450 (1975-1996); Hydroxylases (1979-1996)
- History note
- 97; was DEBRISOQUINE 4-HYDROXYLASE (NM) 1982-96
- Online note
- use CYTOCHROME P-450 CYP2D6 (NM) to search DEBRISOQUINE 4-HYDROXYLASE 1982-96
- Public note
- 97; DEBRISOQUINE 4-HYDROXYLASE was indexed under CYTOCHROME P-450 & HYDROXYLASES 1982-96
Combination
- antagonists & inhibitors
- Cytochrome P-450 CYP2D6 Inhibitors
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis 9
- BI
- biosynthesis
- BL
- blood 4
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 3
- CL
- classification
- DF
- deficiency 2
- DE
- drug effects 13
- EC
- economics
- GE
- genetics 44
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification 2
- ME
- metabolism 57
- PK
- pharmacokinetics 7
- PD
- pharmacology 4
- PH
- physiology 9
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 4
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.244.453.005.110
Benzopyrene Hydroxylase
D08.811.682.690.708.170.010.024
7-Alkoxycoumarin O-Dealkylase
D08.811.682.690.708.170.010.110
Benzopyrene Hydroxylase
D12.776.422.220.453.010.110
Benzopyrene Hydroxylase
CYP2D6 protein, human Chemical MeSH Browser