Cytochrome P-450 CYP2B1 [cytochrom P-450 CYP2B1]
topical
4
- Terms
-
BROD
CYP 2B1
CYP2B1
cytochrom P450 2B1
PROD
-
7-Benzyloxyresorufin O-Dealkylase
7-Pentylresorufin O-Depentylase
Benzyloxyresorufin O-Dealkylase
BROD
CYP 2B1
CYP2B1
Cytochrome P450 2B1
Pentoxyresorufin O-Dealkylase
PROD
Persistent link
https://www.medvik.cz/link/D019362
Definition
A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.
- Annotation
- do not confuse with other cytochrome P-450 CYP's
- nepleť s dalšími cytochromy P-450 CYP
- DUI
- D019362 MeSH Browser
- CUI
- M0028816
- Previous indexing
- Cytochrome P-450 (1985-1996); Oxidoreductases (1985-1996)
- History note
- 97; was PENTOXYRESORUFIN O-DEALKYLASE (NM) 1985-96
- Online note
- use CYTOCHROME P-450 CYP2B1 (NM) to search PENTOXYRESORUFIN O-DEALKYLASE 1985-96
- Public note
- 97; PENTOXYRESORUFIN O-DEALKYLASE was indexed under CYTOCHROME P-450 & OXIDOREDUCTASES 1985-96
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors 2
- BI
- biosynthesis 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.244.453.005.110
Benzopyrene Hydroxylase
D08.811.682.690.708.170.010.024
7-Alkoxycoumarin O-Dealkylase
D08.811.682.690.708.170.010.110
Benzopyrene Hydroxylase
D12.776.422.220.453.010.110
Benzopyrene Hydroxylase