An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.

Annotation

do not confuse with other cytochrome P-450 CYP's

nepleť s dalšími cytochromy P-450 CYP

DUI

D019392 MeSH Browser

CUI

M0028857

Previous indexing

Oxidoreductases (1972-1974); Cytochrome P-450 (1975-1996); Hydroxylases (1984-1996); Nitrosamines (1972-1976); Oxidoreductases, N-Demethylating (1975-1996)

History note

97; was DIMETHYLNITROSAMIME N-DEMETHYLASE (NM) 1972-96 & was 4-NITROPHENOL-2-HYDROXYLASE (NM) 1984-96

Online note

use CYTOCHROME P-450 CYP2E1 (NM) to search DIMETHYLNITROSAMINE N-DEMETHYLASE 1980-96 & 4-NITROPHENOL-2-HYDROXYLASE 1984-96

Public note

97; DIMETHYLNITROSAMINE N-DEMETHYLASE was indexed under CYTOCHROME P-450 & OXIDOREDUCTASES, N-DEMETHYLATING 1975-96, NITROSAMINES 1972-76, & OXIDOREDUCTASES 1972-74; 4-NITROPHENOL-2-HYDROXYLASE was indexed under CYTOCHROME P-450 & HYDROXYLASES 1984-96