Cytochrome P-450 CYP3A [cytochrom P-450 CYP3A]

topical
132
Terms

CYP3A
CYP3A4
CYP3A5
cytochrom P-450 CYP3A4
cytochrom P-450 CYP3A5
cytochrom P-450IIIA
cytochrom P450 3A
cytochrom P450 3A4
cytochrom P450 3A5
erythromycin-N-demethylasa

 

CYP3A
CYP3A4
CYP3A5
Cytochrome P-450 CYP3A4
Cytochrome P-450 CYP3A5
Cytochrome P-450IIIA
Cytochrome P450 3A
Cytochrome P450 3A4
Cytochrome P450 3A5
Erythromycin N-Demethylase
Taurochenodeoxycholate 6-alpha-Monooxygenase

Persistent link   https://www.medvik.cz/link/D051544
Definition

A cytochrome P-450 suptype that has specificity for a broad variety of lipophilic compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN.

DUI
D051544 MeSH Browser
CUI
M0082919
History note
2006(1980)
Public note
2006; CYTOCHROME P-450 CYP3A was indexed under ARYL HYDROCARBON HYDROXYLASES & OXIDOREDUCTASES, N-DEMETHYLATING 1980-2005

Combination

antagonists & inhibitors
Cytochrome P-450 CYP3A Inhibitors

Allowable subheadings

AD
administration & dosage
AE
adverse effects 2
AN
analysis 1
BI
biosynthesis 6
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 8
CL
classification
DF
deficiency
DE
drug effects 18
EC
economics
GE
genetics 42
HI
history
IM
immunology 1
IP
isolation & purification 1
ME
metabolism 81
PK
pharmacokinetics 2
PD
pharmacology 3
PH
physiology 3
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 1
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.244 Cytochromes 121
D08.244.453 Cytochrome P-450 Enzyme System 694
D08.244.453.860 Cytochrome P450 Family 3 1
D08.244.453.860.500 Cytochrome P-450 CYP3A 132
D08.811 Enzymes 1 554
D08.811.682 Oxidoreductases 448
D08.811.682.662 Oxidoreductases Acting on CH-NH Group Donors 7
D08.811.682.662.582 Oxidoreductases, N-Demethylating 10
D08.811.682.662.582.138 AlkB Homolog 4, Lysine Demethylase
D08.811.682.662.582.207 AlkB Homolog 5, RNA Demethylase 4
D08.811.682.662.582.242 Alpha-Ketoglutarate-Dependent Dioxygenase FTO 21
D08.811.682.662.582.276 Aminopyrine N-Demethylase
D08.811.682.662.582.338 Cytochrome P-450 CYP2E1 39
D08.811.682.662.582.353 Cytochrome P-450 CYP3A 132
D08.811.682.662.582.361 Dihydropteridine Reductase 1
D08.811.682.662.582.369 Dimethylglycine Dehydrogenase
D08.811.682.662.582.400 Ethylmorphine-N-Demethylase
D08.811.682.662.582.475 Histone Demethylases 17
D08.811.682.662.582.550 Sarcosine Dehydrogenase 1
D08.811.682.662.582.700 Sarcosine Oxidase 1
D08.811.682.690 Oxygenases 77
D08.811.682.690.708 Mixed Function Oxygenases 68
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System 694
D08.811.682.690.708.170.495 Cytochrome P450 Family 3 1
D08.811.682.690.708.170.495.500 Cytochrome P-450 CYP3A 132
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 584
D12.776.422 Hemeproteins 16
D12.776.422.220 Cytochromes 121
D12.776.422.220.453 Cytochrome P-450 Enzyme System 694
D12.776.422.220.453.860 Cytochrome P450 Family 3 1
D12.776.422.220.453.860.500 Cytochrome P-450 CYP3A 132

CYP3A protein, human Chemical MeSH Browser

CYP3A protein, mouse Chemical MeSH Browser

CYP3A1 protein, mouse Chemical MeSH Browser

CYP3A4 protein, human Chemical MeSH Browser

CYP3A5 protein, human Chemical MeSH Browser

CYP3A7 protein, human Chemical MeSH Browser

Cyp3a11 protein, mouse Chemical MeSH Browser

Cyp3a13 protein, mouse Chemical MeSH Browser

Cyp3a2 protein, rat Chemical MeSH Browser

Cyp3a23-3a1 protein, rat Chemical MeSH Browser

Cyp3a25 protein, mouse Chemical MeSH Browser

cytochrome P450 3A4, mouse Chemical MeSH Browser

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